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CHEBI:6128 - ketoprofen
| Formula | C16H14O3 |
| Net Charge | 0 |
| Average Mass | 254.285 |
| Monoisotopic Mass | 254.09429 |
| SMILES | CC(C(=O)O)c1cccc(C(=O)c2ccccc2)c1 |
| InChI | InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) |
| InChIKey | DKYWVDODHFEZIM-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. drug allergen Any drug which causes the onset of an allergic reaction. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. |
| Applications: | antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-inflammatory agent Any compound that has anti-inflammatory effects. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. drug allergen Any drug which causes the onset of an allergic reaction. antirheumatic drug A drug used to treat rheumatoid arthritis. vulnerary A drug used in treating and healing of wounds. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| ketoprofen (CHEBI:6128) has functional parent propionic acid (CHEBI:30768) |
| ketoprofen (CHEBI:6128) has role analgesic (CHEBI:35480) |
| ketoprofen (CHEBI:6128) has role anti-inflammatory agent (CHEBI:67079) |
| ketoprofen (CHEBI:6128) has role antibacterial agent (CHEBI:33282) |
| ketoprofen (CHEBI:6128) has role antineoplastic agent (CHEBI:35610) |
| ketoprofen (CHEBI:6128) has role antipyretic (CHEBI:35493) |
| ketoprofen (CHEBI:6128) has role antirheumatic drug (CHEBI:35842) |
| ketoprofen (CHEBI:6128) has role drug allergen (CHEBI:88188) |
| ketoprofen (CHEBI:6128) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| ketoprofen (CHEBI:6128) has role environmental contaminant (CHEBI:78298) |
| ketoprofen (CHEBI:6128) has role immunosuppressive agent (CHEBI:35705) |
| ketoprofen (CHEBI:6128) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| ketoprofen (CHEBI:6128) has role vulnerary (CHEBI:73336) |
| ketoprofen (CHEBI:6128) has role xenobiotic (CHEBI:35703) |
| ketoprofen (CHEBI:6128) is a benzophenones (CHEBI:22726) |
| ketoprofen (CHEBI:6128) is a oxo monocarboxylic acid (CHEBI:35871) |
| IUPAC Name |
|---|
| 2-(3-benzoylphenyl)propanoic acid |
| INN | Source |
|---|---|
| ketoprofeno | WHO MedNet |
| Synonyms | Source |
|---|---|
| 19583RP | ChEMBL |
| 2-(3-Benzoylphenyl)propionic acid | ChemIDplus |
| 3-Benzoylhydratropic acid | ChemIDplus |
| 3-Benzoyl-α-methylbenzeneacetic acid | NIST Chemistry WebBook |
| Actron ketoprofen | ChEMBL |
| Aneol | ChEMBL |
| Brand Names | Source |
|---|---|
| Alrheumat | ChEMBL |
| Axorid | ChEMBL |
| Fenoket 200 | ChEMBL |
| Jomethid xl | ChEMBL |
| Ketocid 200 | ChEMBL |
| Ketonal | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1528 | DrugCentral |
| C01716 | KEGG COMPOUND |
| D00132 | KEGG DRUG |
| DB01009 | DrugBank |
| HMDB0015144 | HMDB |
| Ketoprofen | Wikipedia |
| LSM-1955 | LINCS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:2216071 | Reaxys |
| CAS:22071-15-4 | NIST Chemistry WebBook |
| CAS:22071-15-4 | KEGG COMPOUND |
| CAS:22071-15-4 | ChemIDplus |
| Citations |
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