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CHEBI:61076 - belinostat

ChEBI IDCHEBI:61076
ChEBI Namebelinostat
Stars
DefinitionA hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
Last Modified4 March 2015
SubmitterSandra Orchard
DownloadsMolfile
FormulaC15H14N2O4S
Net Charge0
Average Mass318.354
Monoisotopic Mass318.06743
SMILESO=C(/C=C/c1cccc(S(=O)(=O)Nc2ccccc2)c1)NO
InChIInChI=1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+
InChIKeyNCNRHFGMJRPRSK-MDZDMXLPSA-N
Wikipedia
Roles Classification
Biological Role:
EC 3.5.1.98 (histone deacetylase) inhibitor  An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98).
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
belinostat (CHEBI:61076) has role antineoplastic agent (CHEBI:35610)
belinostat (CHEBI:61076) has role EC 3.5.1.98 (histone deacetylase) inhibitor (CHEBI:61115)
belinostat (CHEBI:61076) is a hydroxamic acid (CHEBI:24650)
belinostat (CHEBI:61076) is a olefinic compound (CHEBI:78840)
belinostat (CHEBI:61076) is a sulfonamide (CHEBI:35358)
IUPAC Name 
(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
INN  Source
belinostatKEGG DRUG
Synonyms  Source
PXD101SUBMITTER
N-Hydroxy-3-(3-(phenylsulfamoyl)phenyl)prop-2-enamideChemIDplus
(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]acrylamideIUPAC
Manual XrefsDatabases
D08870KEGG DRUG
BelinostatWikipedia
Registry NumbersSources
Reaxys:10087570Reaxys
CAS:414864-00-9ChemIDplus
Citations