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CHEBI:61022 - naproxol

ChEBI IDCHEBI:61022
ChEBI Namenaproxol
Stars
DefinitionAn aromatic ether in which the substituents on oxygen are 6-[(2S)-1-hydroxypropan-2-yl]-2-naphthyl and methyl.
Last Modified25 February 2016
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC14H16O2
Net Charge0
Average Mass216.280
Monoisotopic Mass216.11503
SMILESCOc1ccc2cc([C@H](C)CO)ccc2c1
InChIInChI=1S/C14H16O2/c1-10(9-15)11-3-4-13-8-14(16-2)6-5-12(13)7-11/h3-8,10,15H,9H2,1-2H3/t10-/m1/s1
InChIKeyLTRANDSQVZFZDG-SNVBAGLBSA-N
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
naproxol (CHEBI:61022) has role antipyretic (CHEBI:35493)
naproxol (CHEBI:61022) has role non-narcotic analgesic (CHEBI:35481)
naproxol (CHEBI:61022) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
naproxol (CHEBI:61022) is a aromatic ether (CHEBI:35618)
IUPAC Name 
(2S)-2-(6-methoxy-2-naphthyl)propan-1-ol
INN  Source
naproxolKEGG DRUG
Synonyms  Source
(−)-2-(6-methoxy-2-naphthyl)-1-propanolChemIDplus
(S)-(−)-2-(6-methoxy-2-naphthyl)-1-propanolChemIDplus
(−)-6-methoxy-β-methyl-2-naphthaleneethanolChemIDplus
(−)-(S)-6-methoxy-β-methyl-2-naphthaleneethanolChemIDplus
Manual XrefsDatabases
D05121KEGG DRUG
LSM-2742LINCS
Registry NumbersSources
Reaxys:7702132Reaxys
CAS:26159-36-4ChemIDplus