CHEBI:60805 - rolicyclidine

ChEBI IDCHEBI:60805
ChEBI Namerolicyclidine
Stars
DefinitionPyrrolidine in which the hydrogen attached to the nitrogen is substituted by a 1-phenylcyclohex-1-yl group.
Last Modified13 December 2010
SubmitterGareth Owen
DownloadsMolfile
FormulaC16H23N
Net Charge0
Average Mass229.367
Monoisotopic Mass229.18305
SMILESc1ccc(C2(N3CCCC3)CCCCC2)cc1
InChIInChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2
InChIKeyFYOWWXMGDATDQY-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
NMDA receptor antagonist  Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
Applications:
general anaesthetic  Substance that produces loss of consciousness.
hallucinogen  Drugs capable of inducing illusions, hallucinations, delusions, paranoid ideations and other alterations of mood and thinking.
ChEBI Ontology
Outgoing Relation(s)
rolicyclidine (CHEBI:60805) has role general anaesthetic (CHEBI:38869)
rolicyclidine (CHEBI:60805) has role hallucinogen (CHEBI:35499)
rolicyclidine (CHEBI:60805) has role NMDA receptor antagonist (CHEBI:60643)
rolicyclidine (CHEBI:60805) is a pyrrolidines (CHEBI:38260)
rolicyclidine (CHEBI:60805) is a tertiary amine (CHEBI:32876)
IUPAC Name 
1-(1-phenylcyclohexyl)pyrrolidine
INNs  Source
rolicyclidinumChemIDplus
roliciclidinaChemIDplus
rolicyclidineChemIDplus
Synonym  Source
PCPyChemIDplus
Manual XrefsDatabases
DB01549DrugBank
Registry NumbersSources
Reaxys:1428458Reaxys
CAS:2201-39-0ChemIDplus