ivermectin (CHEBI:6078)

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CHEBI:6078 - ivermectin

ChEBI ID	CHEBI:6078
ChEBI Name	ivermectin
Stars
Definition	A mixture consisting of ≥ 90% 22,23-dihydroavermectin B_1a (R = Me) and ≤ 10% 22,23-dihydroavermectin B_1b (R = H). A semi-synthetic derivative of abamectin, it is used as a broad-spectrum antiparasite medication, particularly against worms (except tapeworms), although it is also effective against most mites and some lice.
Last Modified	23 November 2020
Downloads	Molfile

Formula	C47H71O14R
Net Charge	0
Average Mass (excl. R groups)	860.060
Monoisotopic Mass (excl. R groups)	859.48438
SMILES	*C[C@H](C)[C@@]1([H])O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@]([H])(C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3\CO[C@]4([H])[C@H](O)C(C)=C[C@@]([H])(C(=O)O1)[C@]34O)O2

Wikipedia

Roles Classification

Biological Role:

antiprotozoal drug Any antimicrobial drug which is used to treat or prevent protozoal infections.

Applications:

anthelminthic drug Substance intended to kill parasitic worms (helminths).

insecticide Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.

antiprotozoal drug Any antimicrobial drug which is used to treat or prevent protozoal infections.

antinematodal drug A substance used in the treatment or control of nematode infestations.

scabicide An acaricide that kills mites of the genus Sarcoptes.

ChEBI Ontology

Outgoing Relation(s)
	ivermectin (CHEBI:6078) has part 22,23-dihydroavermectin B_1a (CHEBI:63941)
	ivermectin (CHEBI:6078) has part 22,23-dihydroavermectin B_1b (CHEBI:63943)
	ivermectin (CHEBI:6078) has role anthelminthic drug (CHEBI:35443)
	ivermectin (CHEBI:6078) has role antinematodal drug (CHEBI:35444)
	ivermectin (CHEBI:6078) has role antiprotozoal drug (CHEBI:35820)
	ivermectin (CHEBI:6078) has role insecticide (CHEBI:24852)
	ivermectin (CHEBI:6078) has role scabicide (CHEBI:73333)
	ivermectin (CHEBI:6078) is a mixture (CHEBI:60004)

INNs	Source
ivermectino	ChemIDplus
ivermectin	ChemIDplus
ivermectine	ChemIDplus
ivermectinum	ChemIDplus

Brand Names	Source
Stromectol	DrugBank
Mectizan	DrugBank
Ivomec	ChemIDplus
Zimecterin	ChEBI
Privermectin	ChEBI
Ivermax	ChEBI

Manual Xrefs	Databases
D00804	KEGG DRUG
Ivermectin	Wikipedia
DB00602	DrugBank
US4199569	Patent
ivermectin	Alan Wood's Pesticides
1455	VSDB
7988461	ChemSpider

Registry Numbers	Sources
CAS:70288-86-7	KEGG COMPOUND
CAS:70288-86-7	ChemIDplus

Citations