porfimer (CHEBI:60652)

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CHEBI:60652 - porfimer

ChEBI ID	CHEBI:60652
ChEBI Name	porfimer
Stars
Definition	The purified component of haematoporphyrin derivative, it consists of a mixture of oligomeric porphyrins formed by ether and ester linkages of up to eight porphyrin units (n = 0-6), where R = CH(OH)Me and/or CH=CH₂.
Last Modified	21 March 2019
Submitter	Gareth Owen
Downloads	Molfile

Formula	(C32H33N4O4R)0-6.C64H68N8O9R2
Net Charge	0
Average Mass (excl. R groups)	0.000
Monoisotopic Mass (excl. R groups)	0.00000
SMILES	C1=C(C)C2Cc3nc(c(C)c3C(C)OC(=O)CCc3c(C)/c4n/c3=C\C3=N/C(=C\c5nc(c(C(C)OC(C)c6c7nc(c6C)/C=C6\N=C(/C=c8\n/c(c(C)c8CCC(=O)O)=C\C8=NC(C7)C(C)=C8)C(CCC(=O)O)=C6C)c5C)CC5N=C(/C=4)C(*)=C5C)C(C)=C3CCC(=O)O)/C=C3\N=C(/C=c4\n/c(c(C)c4CCC(=O)O)=C\C1=N2)C(CCC(=O)O)=C3C

Roles Classification

Biological Roles:

antiviral agent A substance that destroys or inhibits replication of viruses.

cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).

Applications:

photosensitizing agent A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.

dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology

Outgoing Relation(s)
	porfimer (CHEBI:60652) has role antineoplastic agent (CHEBI:35610)
	porfimer (CHEBI:60652) has role antiviral agent (CHEBI:22587)
	porfimer (CHEBI:60652) has role dermatologic drug (CHEBI:50177)
	porfimer (CHEBI:60652) has role photosensitizing agent (CHEBI:47868)
	porfimer (CHEBI:60652) is a β-substituted porphyrin (CHEBI:52187)
	porfimer (CHEBI:60652) is conjugate acid of porfimer anion (CHEBI:60774)
Incoming Relation(s)
Incoming Relation(s)	porfimer anion (CHEBI:60774) is conjugate base of porfimer (CHEBI:60652)

Synonym	Source
dihematoporphyrin ether	ChemIDplus

Manual Xrefs	Databases
DB00707	DrugBank

Registry Numbers	Sources
Reaxys:11092519	Reaxys