EMBL-EBI | Chemical Biology | ChEBI
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| Formula | C12H17F3N.Cl |
| Net Charge | 0 |
| Average Mass | 267.722 |
| Monoisotopic Mass | 267.10016 |
| SMILES | CC[NH2+][C@@H](C)Cc1cccc(C(F)(F)F)c1.[Cl-] |
| InChI | InChI=1S/C12H16F3N.ClH/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15;/h4-6,8-9,16H,3,7H2,1-2H3;1H/t9-;/m0./s1 |
| InChIKey | ZXKXJHAOUFHNAS-FVGYRXGTSA-N |
| Roles Classification |
|---|
| Biological Roles: | serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| Applications: | serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. appetite depressant Any agent that is used to decrease appetite. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. appetite depressant Any agent that is used to decrease appetite. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (S)-fenfluramine hydrochloride (CHEBI:59730) has part (S)-fenfluramine (CHEBI:439329) |
| (S)-fenfluramine hydrochloride (CHEBI:59730) has role appetite depressant (CHEBI:50507) |
| (S)-fenfluramine hydrochloride (CHEBI:59730) has role serotonergic agonist (CHEBI:35941) |
| (S)-fenfluramine hydrochloride (CHEBI:59730) has role serotonin uptake inhibitor (CHEBI:50949) |
| (S)-fenfluramine hydrochloride (CHEBI:59730) is a fenfluramine hydrochloride (CHEBI:59729) |
| IUPAC Name |
|---|
| (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-aminium chloride |
| INN | Source |
|---|---|
| dexfenfluramine hydrochloride | ChemIDplus |
| Synonyms | Source |
|---|---|
| (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride | IUPAC |
| dexfenfluramine HCl | ChemIDplus |
| (+)-fenfluramine hydrochloride | ChemIDplus |
| (+)-(S)-N-ethyl-α-methyl-m-(trifluoromethyl)phenethylamine hydrochloride | ChemIDplus |
| dextrofenfluramine hydrochloride | ChEBI |
| dexfenfluramine HCl | ChEBI |