colestipol hydrochloride (CHEBI:59602)

CHEBI:59602 - colestipol hydrochloride

ChEBI ID	CHEBI:59602
ChEBI Name	colestipol hydrochloride
Stars
Definition	The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.
Last Modified	21 March 2019
Submitter	Gareth Owen
Downloads	Molfile

Formula	(C3H5ClO).(C4H13N3).HCl
Net Charge	0
Average Mass	232.155
Monoisotopic Mass	231.09052
SMILES	Cl.ClCC1CO1.NCCNCCN
InChI	InChI=1S/C4H13N3.C3H5ClO.ClH/c5-1-3-7-4-2-6;4-1-3-2-5-3;/h7H,1-6H2;3H,1-2H2;1H
InChIKey	OJBNDADUQQUPLL-UHFFFAOYSA-N

Roles Classification

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

anticholesteremic drug A substance used to lower plasma cholesterol levels.

cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.

ChEBI Ontology

Outgoing Relation(s)
	colestipol hydrochloride (CHEBI:59602) has part colestipol (CHEBI:3814)
	colestipol hydrochloride (CHEBI:59602) has role anticholesteremic drug (CHEBI:35821)
	colestipol hydrochloride (CHEBI:59602) has role antineoplastic agent (CHEBI:35610)
	colestipol hydrochloride (CHEBI:59602) has role cardiovascular drug (CHEBI:35554)
	colestipol hydrochloride (CHEBI:59602) is a hydrochloride (CHEBI:36807)
	colestipol hydrochloride (CHEBI:59602) is a organic molecular entity (CHEBI:50860)

Synonyms	Source
colestipol HCl	ChemIDplus
Colestipol hydrochloride	ChEMBL
copolymer of diethylenetriamine and 1-chloro-2,3-epoxypropane, hydrochloride	ChemIDplus
NSC-147003	ChEMBL

Manual Xrefs	Databases
D02113	KEGG DRUG
DB00375	DrugBank

Registry Numbers	Sources
CAS:37296-80-3	ChemIDplus
CAS:37296-80-3	KEGG DRUG