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CHEBI:59594 - colesevelam

Default Structure
ChEBI IDCHEBI:59594
ChEBI Namecolesevelam
Stars
DefinitionA polyallylamine cross-linked with epichlorohydrin and alkylated with 1-bromodecane and 6-bromohexyltrimethylammonium bromide. It is used as its hydrochloride as an orally administered bile acid sequestrant to reduce the amount of cholesterol and certain fatty substances in the blood.
Last Modified2 July 2010
SubmitterGareth Owen
DownloadsMolfile
Formula(C12H27N2)co.(C14H29N)co.(C3H7N)co.(C9H18N2O)co.Cl
Net Charge0
Average Mass673.560
Monoisotopic Mass672.61604
SMILES*CC(*)CN.*CC(*)CNCC(O)CNCC(*)C*.*CC(*)CNCCCCCCCCCCC.*CC(*)CNCCCCCC[N+](C)(C)C.[Cl-]
Roles Classification
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
anticholesteremic drug  A substance used to lower plasma cholesterol levels.
ChEBI Ontology
Outgoing Relation(s)
colesevelam (CHEBI:59594) has role anticholesteremic drug (CHEBI:35821)
colesevelam (CHEBI:59594) has role cardiovascular drug (CHEBI:35554)
colesevelam (CHEBI:59594) is a quaternary ammonium salt (CHEBI:35273)
colesevelam (CHEBI:59594) is a vinyl polymer macromolecule (CHEBI:53242)
Incoming Relation(s)
colesevelam hydrochloride (CHEBI:59599) has part colesevelam (CHEBI:59594)
INN  Source
colesevelamChemIDplus
Manual XrefsDatabases
D07743KEGG DRUG
DB00930DrugBank
US5693675Patent
WO9534585Patent
Registry NumbersSources
CAS:182815-43-6ChemIDplus