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CHEBI:5959 - irbesartan
| Formula | C25H28N6O |
| Net Charge | 0 |
| Average Mass | 428.540 |
| Monoisotopic Mass | 428.23246 |
| SMILES | CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nnnn2)cc1 |
| InChI | InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30) |
| InChIKey | YOSHYTLCDANDAN-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. antiviral agent A substance that destroys or inhibits replication of viruses. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. hypoglycemic agent A drug which lowers the blood glucose level. angiotensin receptor antagonist A hormone antagonist that blocks angiotensin receptors. renoprotective agent Any compound that is able to prevent damage to the kidneys. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| irbesartan (CHEBI:5959) has role angiotensin receptor antagonist (CHEBI:61016) |
| irbesartan (CHEBI:5959) has role anti-arrhythmia drug (CHEBI:38070) |
| irbesartan (CHEBI:5959) has role antihypertensive agent (CHEBI:35674) |
| irbesartan (CHEBI:5959) has role antiviral agent (CHEBI:22587) |
| irbesartan (CHEBI:5959) has role cardiovascular drug (CHEBI:35554) |
| irbesartan (CHEBI:5959) has role environmental contaminant (CHEBI:78298) |
| irbesartan (CHEBI:5959) has role hypoglycemic agent (CHEBI:35526) |
| irbesartan (CHEBI:5959) has role renoprotective agent (CHEBI:231911) |
| irbesartan (CHEBI:5959) has role xenobiotic (CHEBI:35703) |
| irbesartan (CHEBI:5959) is a azaspiro compound (CHEBI:35624) |
| irbesartan (CHEBI:5959) is a biphenylyltetrazole (CHEBI:48420) |
| IUPAC Name |
|---|
| 2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one |
| INN | Source |
|---|---|
| irbesartan | ChemIDplus |
| Synonyms | Source |
|---|---|
| 2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one | IUPAC |
| BMS 186295 | ChemIDplus |
| BMS-186295 | ChEMBL |
| Irbesartan | KEGG COMPOUND |
| Irbesartan bms | ChEMBL |
| Irbesartan teva | ChEMBL |
| Brand Names | Source |
|---|---|
| Avapro | KEGG DRUG |
| Irbesartan component of avalide | ChEMBL |
| Irbesartan component of coaprovel | ChEMBL |
| Irbesartan component of ibersartan/hydrochlorothiazide ibersartan | ChEMBL |
| Irbesartan component of ibersartan/hydrochlorothiazide teva ibersartan | ChEMBL |
| Irbesartan component of ibersartan/hydrochlorothiazide zentiva ibersartan | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:6620400 | Reaxys |
| CAS:138402-11-6 | ChemIDplus |
| CAS:138402-11-6 | KEGG COMPOUND |
| Citations |
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