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CHEBI:59185 - (S)-bevantolol

ChEBI IDCHEBI:59185
ChEBI Name(S)-bevantolol
Stars
ASCII Name(S)-bevantolol
DefinitionThe (S)-enantiomer of bevantolol.
Last Modified24 August 2012
SubmitterGareth Owen
DownloadsMolfile
FormulaC20H27NO4
Net Charge0
Average Mass345.439
Monoisotopic Mass345.19401
SMILESCOc1ccc(CCNC[C@H](O)COc2cccc(C)c2)cc1OC
InChIInChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3/t17-/m0/s1
InChIKeyHXLAFSUPPDYFEO-KRWDZBQOSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
calcium channel blocker  One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
Applications:
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
(S)-bevantolol (CHEBI:59185) is a bevantolol (CHEBI:238698)
(S)-bevantolol (CHEBI:59185) is enantiomer of (R)-bevantolol (CHEBI:59184)
Incoming Relation(s)
(R)-bevantolol (CHEBI:59184) is enantiomer of (S)-bevantolol (CHEBI:59185)
IUPAC Name 
(2S)-1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol
Synonyms  Source
(S)-1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanolChEBI
(S)-1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanolChEBI
(S)-1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-olChEBI
(S)-1-[2-(3,4-dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-olChEBI