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CHEBI:5893 - indapamide
| Formula | C16H16ClN3O3S |
| Net Charge | 0 |
| Average Mass | 365.842 |
| Monoisotopic Mass | 365.06009 |
| SMILES | CC1Cc2ccccc2N1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 |
| InChI | InChI=1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23) |
| InChIKey | NDDAHWYSQHTHNT-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
|---|
| Biological Role: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. hypoglycemic agent A drug which lowers the blood glucose level. diuretic An agent that promotes the excretion of urine through its effects on kidney function. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| indapamide (CHEBI:5893) has functional parent benzamide (CHEBI:28179) |
| indapamide (CHEBI:5893) has role antihypertensive agent (CHEBI:35674) |
| indapamide (CHEBI:5893) has role cardiovascular drug (CHEBI:35554) |
| indapamide (CHEBI:5893) has role diuretic (CHEBI:35498) |
| indapamide (CHEBI:5893) has role hypoglycemic agent (CHEBI:35526) |
| indapamide (CHEBI:5893) has role immunosuppressive agent (CHEBI:35705) |
| indapamide (CHEBI:5893) is a indoles (CHEBI:24828) |
| indapamide (CHEBI:5893) is a organochlorine compound (CHEBI:36683) |
| indapamide (CHEBI:5893) is a sulfonamide (CHEBI:35358) |
| IUPAC Name |
|---|
| 4-chloro-N-(2-methyl-2,3-dihydro-1H-indol-1-yl)-3-sulfamoylbenzamide |
| INNs | Source |
|---|---|
| indapamida | DrugBank |
| indapamidum | DrugBank |
| Synonyms | Source |
|---|---|
| Arifon | ChEMBL |
| Bajaten | ChEMBL |
| Damide | ChEMBL |
| Flubest | ChEMBL |
| Fludex | ChEMBL |
| Fludin | ChEMBL |
| Brand Names | Source |
|---|---|
| Cardide sr | ChEMBL |
| Ethibide xl | ChEMBL |
| Indapamide component of br-1015 | ChEMBL |
| Indaxa 2.5 | ChEMBL |
| Indipam xl | ChEMBL |
| Lozol | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:1604026 | Reaxys |
| CAS:26807-65-8 | ChemIDplus |
| Citations |
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