NADPH(4-) (CHEBI:57783)

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CHEBI:57783 - NADPH(4−)

ChEBI ID	CHEBI:57783
ChEBI Name	NADPH(4−)
Stars
ASCII Name	NADPH(4-)
Definition	Tetraanion of NADPH arising from deprotonation of the diphosphate and phosphate OH groups; major species at pH 7.3.
Last Modified	26 July 2019
Downloads	Molfile

Formula	C21H26N7O17P3
Net Charge	-4
Average Mass	741.393
Monoisotopic Mass	741.06200
SMILES	NC(=O)C1=CN([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OP(=O)([O-])[O-])[C@@H]3O)[C@@H](O)[C@H]2O)C=CC1
InChI	InChI=1S/C21H30N7O17P3/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35)/p-4/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChIKey	ACFIXJIJDZMPPO-NNYOXOHSSA-J

Species of Metabolite	Component	Source	Comments
Homo sapiens (ncbitaxon:9606)	-	DOI (10.1038/nbt.2488)
Saccharomyces cerevisiae (ncbitaxon:4932)	-	PubMed (24678285)	Source: yeast.sf.net

Roles Classification

Chemical Role:

electron donor A molecular entity that can transfer an electron to another molecular entity.

Biological Roles:

cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group).

Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).

human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).

ChEBI Ontology

Outgoing Relation(s)
	NADPH(4−) (CHEBI:57783) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
	NADPH(4−) (CHEBI:57783) has role cofactor (CHEBI:23357)
	NADPH(4−) (CHEBI:57783) has role human metabolite (CHEBI:77746)
	NADPH(4−) (CHEBI:57783) is a hydrogen donor (CHEBI:17499)
	NADPH(4−) (CHEBI:57783) is a ribonucleoside triphosphate oxoanion (CHEBI:59724)
	NADPH(4−) (CHEBI:57783) is conjugate base of NADPH (CHEBI:16474)
Incoming Relation(s)
	(S)-NADPHX(4−) (CHEBI:64076) has functional parent NADPH(4−) (CHEBI:57783)
	NADPH (CHEBI:16474) is conjugate acid of NADPH(4−) (CHEBI:57783)

IUPAC Name
2'-O-phosphonatoadenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] diphosphate}

Synonym	Source
NADPH tetraanion	ChEBI

UniProt Name	Source
NADPH	UniProt

Registry Numbers	Sources
Beilstein:10411862	Beilstein