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CHEBI:57454 - 10-formyltetrahydrofolate(2−)

Default Structure
ChEBI IDCHEBI:57454
ChEBI Name10-formyltetrahydrofolate(2−)
Stars
ASCII Name10-formyltetrahydrofolate(2-)
DefinitionDianion of 10-formyltetrahydrofolic acid arising from deprotonation of both carboxylic acid functions.
Last Modified12 July 2023
DownloadsMolfile
FormulaC20H21N7O7
Net Charge-2
Average Mass471.430
Monoisotopic Mass471.15134
SMILES[H]C(=O)N(CC1CNc2nc(N)nc(=O)c2N1)c1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1
InChIInChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32)/p-2/t11?,13-/m0/s1
InChIKeyAUFGTPPARQZWDO-YUZLPWPTSA-L
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - DOI (10.1038/nbt.2488)
Saccharomyces cerevisiae (ncbitaxon:4932) - PubMed (24678285) Source: yeast.sf.net
Roles Classification
Biological Roles:
Saccharomyces cerevisiae metabolite  Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
ChEBI Ontology
Outgoing Relation(s)
10-formyltetrahydrofolate(2−) (CHEBI:57454) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
10-formyltetrahydrofolate(2−) (CHEBI:57454) has role human metabolite (CHEBI:77746)
10-formyltetrahydrofolate(2−) (CHEBI:57454) is a dicarboxylic acid dianion (CHEBI:28965)
10-formyltetrahydrofolate(2−) (CHEBI:57454) is conjugate base of 10-formyltetrahydrofolic acid (CHEBI:15637)
Incoming Relation(s)
(6R)-10-formyltetrahydrofolate(2−) (CHEBI:195366) is a 10-formyltetrahydrofolate(2−) (CHEBI:57454)
(6S)-10-formyltetrahydrofolate(2−) (CHEBI:195367) is a 10-formyltetrahydrofolate(2−) (CHEBI:57454)
10-formyltetrahydrofolic acid (CHEBI:15637) is conjugate acid of 10-formyltetrahydrofolate(2−) (CHEBI:57454)
IUPAC Name 
(2S)-2-(4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl](formyl)amino}benzamido)pentanedioate
Synonyms  Source
10-formyltetrahydrofolateChEBI
10-formyltetrahydrofolate dianionChEBI
10-HCO-H4folateChEBI
UniProt Name  Source
10-formyltetrahydrofolateUniProt