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CHEBI:5721 - hinokiflavone

ChEBI IDCHEBI:5721
ChEBI Namehinokiflavone
Stars
DefinitionA biflavonoid that is apigenin substituted by a 4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy group at position 6. A diflavonyl ether, it is isolated from Rhus succedanea and has been found to possess significant cytotoxic potential.
Secondary ChEBI IDCHEBI:66014
Last Modified28 July 2014
DownloadsMolfile
FormulaC30H18O10
Net Charge0
Average Mass538.464
Monoisotopic Mass538.09000
SMILESO=c1cc(-c2ccc(Oc3c(O)cc4oc(-c5ccc(O)cc5)cc(=O)c4c3O)cc2)oc2cc(O)cc(O)c12
InChIInChI=1S/C30H18O10/c31-16-5-1-14(2-6-16)24-12-21(35)28-26(40-24)13-22(36)30(29(28)37)38-18-7-3-15(4-8-18)23-11-20(34)27-19(33)9-17(32)10-25(27)39-23/h1-13,31-33,36-37H
InChIKeyWTDHMFBJQJSTMH-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Rhus succedanea (ncbitaxon:269721) fruit (BTO:0000486) PubMed (2526343) drupes
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
hinokiflavone (CHEBI:5721) has functional parent apigenin (CHEBI:18388)
hinokiflavone (CHEBI:5721) has role antineoplastic agent (CHEBI:35610)
hinokiflavone (CHEBI:5721) has role metabolite (CHEBI:25212)
hinokiflavone (CHEBI:5721) has role neuroprotective agent (CHEBI:63726)
hinokiflavone (CHEBI:5721) is a aromatic ether (CHEBI:35618)
hinokiflavone (CHEBI:5721) is a biflavonoid (CHEBI:50128)
hinokiflavone (CHEBI:5721) is a hydroxyflavone (CHEBI:24698)
IUPAC Name 
6-[4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)phenoxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Synonyms  Source
HinokiflavoneKEGG COMPOUND
4',6''-O-biapigeninChemIDplus
Manual XrefsDatabases
C10057KEGG COMPOUND
LMPK12040004LIPID MAPS
EP1245230Patent
WO9700679Patent
C00001049KNApSAcK
Registry NumbersSources
Reaxys:379316Reaxys
CAS:19202-36-9KEGG COMPOUND
CAS:19202-36-9ChemIDplus
Citations