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CHEBI:5706 - hexobarbital

ChEBI IDCHEBI:5706
ChEBI Namehexobarbital
Stars
DefinitionA member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
Secondary ChEBI IDCHEBI:102367
Last Modified22 February 2017
DownloadsMolfile
FormulaC12H16N2O3
Net Charge0
Average Mass236.271
Monoisotopic Mass236.11609
SMILESCN1C(=O)NC(=O)C(C)(C2=CCCCC2)C1=O
InChIInChI=1S/C12H16N2O3/c1-12(8-6-4-3-5-7-8)9(15)13-11(17)14(2)10(12)16/h6H,3-5,7H2,1-2H3,(H,13,15,17)
InChIKeyUYXAWHWODHRRMR-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
hexobarbital (CHEBI:5706) has functional parent barbituric acid (CHEBI:16294)
hexobarbital (CHEBI:5706) is a barbiturates (CHEBI:22693)
IUPAC Name 
5-(cyclohex-1-en-1-yl)-1,5-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
Synonyms  Source
HexobarbitoneKEGG COMPOUND
HexobarbitalKEGG COMPOUND
5-(1-cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrioneNIST Chemistry WebBook
5-(1-cyclohexen-1-yl)-1,5-dimethylbarbituric acidNIST Chemistry WebBook
EvipanChemIDplus
methexenylChemIDplus
Manual XrefsDatabases
C11723KEGG COMPOUND
DB01355DrugBank
HexobarbitalWikipedia
HMDB0015444HMDB
D01071KEGG DRUG
1369DrugCentral
Registry NumbersSources
Gmelin:282233Gmelin
Reaxys:253102Reaxys
CAS:56-29-1KEGG COMPOUND
CAS:56-29-1ChemIDplus
CAS:56-29-1NIST Chemistry WebBook
Citations