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CHEBI:5613 - haloperidol
| Formula | C21H23ClFNO2 |
| Net Charge | 0 |
| Average Mass | 375.871 |
| Monoisotopic Mass | 375.14013 |
| SMILES | O=C(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 |
| InChI | InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 |
| InChIKey | LNEPOXFFQSENCJ-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. |
| Applications: | antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. serotonergic antagonist Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists. first generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased. antidyskinesia agent Any compound which can be used to treat or alleviate the symptoms of dyskinesia. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| haloperidol (CHEBI:5613) has role analgesic (CHEBI:35480) |
| haloperidol (CHEBI:5613) has role antidepressant (CHEBI:35469) |
| haloperidol (CHEBI:5613) has role antidyskinesia agent (CHEBI:66956) |
| haloperidol (CHEBI:5613) has role antiemetic (CHEBI:50919) |
| haloperidol (CHEBI:5613) has role anxiolytic drug (CHEBI:35474) |
| haloperidol (CHEBI:5613) has role dopaminergic antagonist (CHEBI:48561) |
| haloperidol (CHEBI:5613) has role first generation antipsychotic (CHEBI:65190) |
| haloperidol (CHEBI:5613) has role serotonergic antagonist (CHEBI:48279) |
| haloperidol (CHEBI:5613) is a aromatic ketone (CHEBI:76224) |
| haloperidol (CHEBI:5613) is a hydroxypiperidine (CHEBI:48590) |
| haloperidol (CHEBI:5613) is a monochlorobenzenes (CHEBI:83403) |
| haloperidol (CHEBI:5613) is a organofluorine compound (CHEBI:37143) |
| haloperidol (CHEBI:5613) is a tertiary alcohol (CHEBI:26878) |
| IUPAC Name |
|---|
| 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one |
| INNs | Source |
|---|---|
| haloperidol | KEGG DRUG |
| haloperidolum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine | ChemIDplus |
| 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one | IUPHAR |
| 4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone | NIST Chemistry WebBook |
| 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone | NIST Chemistry WebBook |
| 4'-fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone | NIST Chemistry WebBook |
| Haloperidol decanoate impurity, haloperidol- | ChEMBL |
| Brand Names | Source |
|---|---|
| Dolpin | ChEMBL |
| Dozic | ChEMBL |
| Fortunan | ChEMBL |
| Haldol | KEGG DRUG |
| Haldol solutab | ChEMBL |
| Haloperidol component of vesalium | ChEMBL |
| Citations |
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