EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:5516 |
| ChEBI Name | sodium aurothiomalate |
| Stars | |
| Definition | A variable mixture of the mono- and di-sodium salts of aurothiomalic acid. It is used for treatment of rheumatoid arthritis. |
| Secondary ChEBI ID | CHEBI:75985 |
| Last Modified | 12 March 2019 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | protease inhibitor A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7). allergen A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. anti-inflammatory agent Any compound that has anti-inflammatory effects. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| sodium aurothiomalate (CHEBI:5516) has part disodium aurothiomalate (CHEBI:35864) |
| sodium aurothiomalate (CHEBI:5516) has part monosodium aurothiomalate (CHEBI:35863) |
| sodium aurothiomalate (CHEBI:5516) has role allergen (CHEBI:50904) |
| sodium aurothiomalate (CHEBI:5516) has role anti-inflammatory agent (CHEBI:67079) |
| sodium aurothiomalate (CHEBI:5516) has role antirheumatic drug (CHEBI:35842) |
| sodium aurothiomalate (CHEBI:5516) has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor (CHEBI:131699) |
| sodium aurothiomalate (CHEBI:5516) has role protease inhibitor (CHEBI:37670) |
| sodium aurothiomalate (CHEBI:5516) is a mixture (CHEBI:60004) |
| Synonyms | Source |
|---|---|
| Gold sodium thiomalate | KEGG DRUG |
| Sodium aurothiomalate | KEGG DRUG |
| Myochrysine (TN) | KEGG DRUG |
| Manual Xrefs | Databases |
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| D00992 | KEGG DRUG |
| Sodium_aurothiomalate | Wikipedia |
| Registry Numbers | Sources |
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| CAS:12244-57-4 | ChemIDplus |
| CAS:12244-57-4 | KEGG DRUG |
| Citations |
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