CHEBI:5516 - sodium aurothiomalate

ChEBI IDCHEBI:5516
ChEBI Namesodium aurothiomalate
Stars
DefinitionA variable mixture of the mono- and di-sodium salts of aurothiomalic acid. It is used for treatment of rheumatoid arthritis.
Secondary ChEBI IDCHEBI:75985
Last Modified12 March 2019
Wikipedia
Roles Classification
Biological Roles:
protease inhibitor  A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases).
EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor  A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
allergen  A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
Applications:
antirheumatic drug  A drug used to treat rheumatoid arthritis.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
ChEBI Ontology
Outgoing Relation(s)
sodium aurothiomalate (CHEBI:5516) has part disodium aurothiomalate (CHEBI:35864)
sodium aurothiomalate (CHEBI:5516) has part monosodium aurothiomalate (CHEBI:35863)
sodium aurothiomalate (CHEBI:5516) has role allergen (CHEBI:50904)
sodium aurothiomalate (CHEBI:5516) has role anti-inflammatory agent (CHEBI:67079)
sodium aurothiomalate (CHEBI:5516) has role antirheumatic drug (CHEBI:35842)
sodium aurothiomalate (CHEBI:5516) has role EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor (CHEBI:131699)
sodium aurothiomalate (CHEBI:5516) has role protease inhibitor (CHEBI:37670)
sodium aurothiomalate (CHEBI:5516) is a mixture (CHEBI:60004)
Synonyms  Source
Gold sodium thiomalateKEGG DRUG
Sodium aurothiomalateKEGG DRUG
Myochrysine (TN)KEGG DRUG
Manual XrefsDatabases
D00992KEGG DRUG
Sodium_aurothiomalateWikipedia
Registry NumbersSources
CAS:12244-57-4ChemIDplus
CAS:12244-57-4KEGG DRUG
Citations