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CHEBI:53289 - donepezil
| Formula | C24H29NO3 |
| Net Charge | 0 |
| Average Mass | 379.500 |
| Monoisotopic Mass | 379.21474 |
| SMILES | [H]C1(CC2CCN(Cc3ccccc3)CC2)Cc2cc(OC)c(OC)cc2C1=O |
| InChI | InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3 |
| InChIKey | ADEBPBSSDYVVLD-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | EC 3.1.1.7 (acetylcholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. EC 3.1.1.8 (cholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8). |
| Application: | nootropic agent Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| donepezil (CHEBI:53289) has part (R)-donepezil (CHEBI:53292) |
| donepezil (CHEBI:53289) has part (S)-donepezil (CHEBI:53290) |
| donepezil (CHEBI:53289) has role EC 3.1.1.7 (acetylcholinesterase) inhibitor (CHEBI:38462) |
| donepezil (CHEBI:53289) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733) |
| donepezil (CHEBI:53289) has role nootropic agent (CHEBI:66980) |
| donepezil (CHEBI:53289) is a racemate (CHEBI:60911) |
| donepezil (CHEBI:53289) is conjugate base of donepezil (1+) (CHEBI:145498) |
| Incoming Relation(s) |
| donepezil (1+) (CHEBI:145498) is conjugate acid of donepezil (CHEBI:53289) |
| INNs | Source |
|---|---|
| donepezil | ChemIDplus |
| donépézil | WHO MedNet |
| donepezilo | WHO MedNet |
| donepezilum | WHO MedNet |