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CHEBI:5138 - fluvoxamine

Default Structure
ChEBI IDCHEBI:5138
ChEBI Namefluvoxamine
Stars
DefinitionAn oxime O-ether that is benzene substituted by a (1E)-N-(2-aminoethoxy)-5-methoxypentanimidoyl group at position 1 and a trifluoromethyl group at position 4. It is a selective serotonin reuptake inhibitor that is used for the treatment of obsessive-compulsive disorder.
Last Modified1 February 2021
DownloadsMolfile
FormulaC15H21F3N2O2
Net Charge0
Average Mass318.339
Monoisotopic Mass318.15551
SMILESCOCCCC/C(=N\OCCN)c1ccc(C(F)(F)F)cc1
InChIInChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+
InChIKeyCJOFXWAVKWHTFT-XSFVSMFZSA-N
Wikipedia
Roles Classification
Biological Role:
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
Applications:
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
ChEBI Ontology
Outgoing Relation(s)
fluvoxamine (CHEBI:5138) has functional parent (trifluoromethyl)benzene (CHEBI:36810)
fluvoxamine (CHEBI:5138) has role antidepressant (CHEBI:35469)
fluvoxamine (CHEBI:5138) has role anxiolytic drug (CHEBI:35474)
fluvoxamine (CHEBI:5138) has role serotonin uptake inhibitor (CHEBI:50949)
fluvoxamine (CHEBI:5138) is a (trifluoromethyl)benzenes (CHEBI:83565)
fluvoxamine (CHEBI:5138) is a 5-methoxyvalerophenone O-(2-aminoethyl)oxime (CHEBI:36815)
IUPAC Name 
(1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan-1-one O-(2-aminoethyl)oxime
INNs  Source
fluvoxaminaWHO MedNet
fluvoxamineChemIDplus
fluvoxamineWHO MedNet
fluvoxaminumWHO MedNet
Synonyms  Source
2-{[(E)-{5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}amino]oxy}ethan-1-amineIUPAC
O-(2-aminoethyl)-N-{(1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene}hydroxylamineIUPAC
FluvoxamineKEGG COMPOUND
Manual XrefsDatabases
1230DrugCentral
4481878ChemSpider
C07571KEGG COMPOUND
CPD-20520MetaCyc
D07984KEGG DRUG
DB00176DrugBank
FluvoxamineWikipedia
FVXPDBeChem
HMDB0014322HMDB
NL7503310Patent
US4085225Patent
Registry NumbersSources
Beilstein:5583954Beilstein
CAS:54739-18-3NIST Chemistry WebBook
CAS:54739-18-3ChemIDplus
CAS:54739-18-3KEGG COMPOUND
Citations