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CHEBI:51141 - alfuzosin
| Formula | C19H27N5O4 |
| Net Charge | 0 |
| Average Mass | 389.456 |
| Monoisotopic Mass | 389.20630 |
| SMILES | COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC |
| InChI | InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23) |
| InChIKey | WNMJYKCGWZFFKR-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Role: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| alfuzosin (CHEBI:51141) has role antihypertensive agent (CHEBI:35674) |
| alfuzosin (CHEBI:51141) has role antineoplastic agent (CHEBI:35610) |
| alfuzosin (CHEBI:51141) has role α-adrenergic antagonist (CHEBI:37890) |
| alfuzosin (CHEBI:51141) is a monocarboxylic acid amide (CHEBI:29347) |
| alfuzosin (CHEBI:51141) is a quinazolines (CHEBI:38530) |
| alfuzosin (CHEBI:51141) is a tetrahydrofuranol (CHEBI:47017) |
| Incoming Relation(s) |
| alfuzosin hydrochloride (CHEBI:32286) has part alfuzosin (CHEBI:51141) |
| IUPAC Name |
|---|
| N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide |
| INNs | Source |
|---|---|
| alfuzosin | WHO MedNet |
| alfuzosina | WHO MedNet |
| alfuzosine | WHO MedNet |
| alfuzosinum | WHO MedNet |