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CHEBI:51141 - alfuzosin
| Formula | C19H27N5O4 |
| Net Charge | 0 |
| Average Mass | 389.456 |
| Monoisotopic Mass | 389.20630 |
| SMILES | COc1cc2nc(N(C)CCCNC(=O)C3CCCO3)nc(N)c2cc1OC |
| InChI | InChI=1S/C19H27N5O4/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23) |
| InChIKey | WNMJYKCGWZFFKR-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Role: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. |
| Applications: | antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| alfuzosin (CHEBI:51141) has role antihypertensive agent (CHEBI:35674) |
| alfuzosin (CHEBI:51141) has role antineoplastic agent (CHEBI:35610) |
| alfuzosin (CHEBI:51141) has role α-adrenergic antagonist (CHEBI:37890) |
| alfuzosin (CHEBI:51141) is a monocarboxylic acid amide (CHEBI:29347) |
| alfuzosin (CHEBI:51141) is a quinazolines (CHEBI:38530) |
| alfuzosin (CHEBI:51141) is a tetrahydrofuranol (CHEBI:47017) |
| Incoming Relation(s) |
| alfuzosin hydrochloride (CHEBI:32286) has part alfuzosin (CHEBI:51141) |
| IUPAC Name |
|---|
| N-{3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl}tetrahydrofuran-2-carboxamide |
| INNs | Source |
|---|---|
| alfuzosin | WHO MedNet |
| alfuzosina | WHO MedNet |
| alfuzosine | WHO MedNet |
| alfuzosinum | WHO MedNet |