CHEBI:51038 - minaprine

ChEBI IDCHEBI:51038
ChEBI Nameminaprine
Stars
Last Modified22 February 2017
SubmitterInma Spiteri
DownloadsMolfile
FormulaC17H22N4O
Net Charge0
Average Mass298.390
Monoisotopic Mass298.17936
SMILESCc1cc(-c2ccccc2)nnc1NCCN1CCOCC1
InChIInChI=1S/C17H22N4O/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21/h2-6,13H,7-12H2,1H3,(H,18,20)
InChIKeyLDMWSLGGVTVJPG-UHFFFAOYSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
cholinergic drug  Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
Applications:
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
serotonin uptake inhibitor  A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
cholinergic drug  Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
ChEBI Ontology
Outgoing Relation(s)
minaprine (CHEBI:51038) has role antidepressant (CHEBI:35469)
minaprine (CHEBI:51038) has role antiparkinson drug (CHEBI:48407)
minaprine (CHEBI:51038) has role cholinergic drug (CHEBI:38323)
minaprine (CHEBI:51038) has role dopamine uptake inhibitor (CHEBI:51039)
minaprine (CHEBI:51038) has role serotonin uptake inhibitor (CHEBI:50949)
minaprine (CHEBI:51038) is a morpholines (CHEBI:38785)
minaprine (CHEBI:51038) is a pyridazines (CHEBI:37921)
minaprine (CHEBI:51038) is a secondary amine (CHEBI:32863)
Incoming Relation(s)
minaprine hydrochloride (CHEBI:51040) has part minaprine (CHEBI:51038)
IUPAC Name 
4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine
INNs  Source
minaprineChEBI
minaprinaChEBI
minaprinumChEBI
Synonyms  Source
4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholineChemIDplus
4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazinChemIDplus
N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamineChemIDplus
Manual XrefsDatabases
D05039KEGG DRUG
DB00805DrugBank
DE2229215Patent
US4169158Patent
LSM-2037LINCS
1812DrugCentral
Registry NumbersSources
Beilstein:1219740Beilstein
CAS:25905-77-5ChemIDplus