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CHEBI:50727 - mitoxantrone dihydrochloride
| Formula | C22H28N4O6.2HCl |
| Net Charge | 0 |
| Average Mass | 517.410 |
| Monoisotopic Mass | 516.15424 |
| SMILES | Cl.Cl.O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21 |
| InChI | InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H |
| InChIKey | ZAHQPTJLOCWVPG-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mitoxantrone dihydrochloride (CHEBI:50727) has part mitoxantrone (CHEBI:50729) |
| mitoxantrone dihydrochloride (CHEBI:50727) has role analgesic (CHEBI:35480) |
| mitoxantrone dihydrochloride (CHEBI:50727) has role antineoplastic agent (CHEBI:35610) |
| mitoxantrone dihydrochloride (CHEBI:50727) has role immunosuppressive agent (CHEBI:35705) |
| mitoxantrone dihydrochloride (CHEBI:50727) is a hydrochloride (CHEBI:36807) |
| IUPAC Name |
|---|
| 1,4-dihydroxy-5,8-bis({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione dihydrochloride |
| Synonyms | Source |
|---|---|
| CL 232,315 | ChEMBL |
| CL-232315 | ChEMBL |
| Mitoxantrone dihcl | ChEMBL |
| mitoxantrone hydrochloride | ChEMBL |
| Mitoxantrone hydrochloride | ChemIDplus |
| NSC-301739 | ChEMBL |
| Brand Names | Source |
|---|---|
| Novantron | DrugBank |
| Novantrone | DrugBank |
| Registry Numbers | Sources |
|---|---|
| Beilstein:4835931 | Beilstein |
| CAS:70476-82-3 | ChemIDplus |
| Citations |
|---|