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CHEBI:50223 - (+)-dexrazoxane

Default Structure
ChEBI IDCHEBI:50223
ChEBI Name(+)-dexrazoxane
Stars
Last Modified22 February 2017
SubmitterInma Spiteri
DownloadsMolfile
FormulaC11H16N4O4
Net Charge0
Average Mass268.273
Monoisotopic Mass268.11715
SMILESC[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
InChIInChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKeyBMKDZUISNHGIBY-ZETCQYMHSA-N
Wikipedia
Roles Classification
Chemical Roles:
chelator  A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Applications:
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
(+)-dexrazoxane (CHEBI:50223) has role antineoplastic agent (CHEBI:35610)
(+)-dexrazoxane (CHEBI:50223) has role cardiovascular drug (CHEBI:35554)
(+)-dexrazoxane (CHEBI:50223) has role chelator (CHEBI:38161)
(+)-dexrazoxane (CHEBI:50223) has role immunosuppressive agent (CHEBI:35705)
(+)-dexrazoxane (CHEBI:50223) is a razoxane (CHEBI:50225)
Incoming Relation(s)
dexrazoxane hydrochloride (CHEBI:50224) has part (+)-dexrazoxane (CHEBI:50223)
IUPAC Name 
4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione
INNs  Source
dexrazoxaneChemIDplus
dexrazoxanoChemIDplus
dexrazoxanumChemIDplus
Synonyms  Source
(+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propaneChemIDplus
DextrorazoxaneDrugBank
(+)-(S)-4,4'-Propylenedi-2,6-piperazinedioneChemIDplus
Manual XrefsDatabases
839DrugCentral
D03730KEGG DRUG
DB00380DrugBank
DexrazoxaneWikipedia
LSM-5248LINCS
Registry NumbersSources
Beilstein:6658412Beilstein
Beilstein:8441732Beilstein
CAS:24584-09-6ChemIDplus