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CHEBI:50223 - (+)-dexrazoxane

ChEBI IDCHEBI:50223
ChEBI Name(+)-dexrazoxane
Stars
Last Modified22 February 2017
SubmitterInma Spiteri
DownloadsMolfile
FormulaC11H16N4O4
Net Charge0
Average Mass268.273
Monoisotopic Mass268.11715
SMILESC[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
InChIInChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKeyBMKDZUISNHGIBY-ZETCQYMHSA-N
Wikipedia
Roles Classification
Chemical Roles:
chelator  A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Applications:
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
(+)-dexrazoxane (CHEBI:50223) has role antineoplastic agent (CHEBI:35610)
(+)-dexrazoxane (CHEBI:50223) has role cardiovascular drug (CHEBI:35554)
(+)-dexrazoxane (CHEBI:50223) has role chelator (CHEBI:38161)
(+)-dexrazoxane (CHEBI:50223) has role immunosuppressive agent (CHEBI:35705)
(+)-dexrazoxane (CHEBI:50223) is a razoxane (CHEBI:50225)
Incoming Relation(s)
dexrazoxane hydrochloride (CHEBI:50224) has part (+)-dexrazoxane (CHEBI:50223)
IUPAC Name 
4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione
INNs  Source
dexrazoxaneChemIDplus
dexrazoxanoChemIDplus
dexrazoxanumChemIDplus
Synonyms  Source
DextrorazoxaneDrugBank
(+)-(S)-4,4'-Propylenedi-2,6-piperazinedioneChemIDplus
(+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propaneChemIDplus
Manual XrefsDatabases
D03730KEGG DRUG
DB00380DrugBank
DexrazoxaneWikipedia
LSM-5248LINCS
839DrugCentral
Registry NumbersSources
Beilstein:6658412Beilstein
Beilstein:8441732Beilstein
CAS:24584-09-6ChemIDplus