CHEBI:5002 - fenoldopam

ChEBI IDCHEBI:5002
ChEBI Namefenoldopam
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Last Modified22 February 2017
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FormulaC16H16ClNO3
Net Charge0
Average Mass305.761
Monoisotopic Mass305.08187
SMILESOc1ccc(C2CNCCc3c2cc(O)c(O)c3Cl)cc1
InChIInChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2
InChIKeyTVURRHSHRRELCG-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
dopamine agonist  A drug that binds to and activates dopamine receptors.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
alpha-adrenergic agonist  An agent that selectively binds to and activates α-adrenergic receptors.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
dopamine agonist  A drug that binds to and activates dopamine receptors.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
fenoldopam (CHEBI:5002) has role antihypertensive agent (CHEBI:35674)
fenoldopam (CHEBI:5002) has role cardiovascular drug (CHEBI:35554)
fenoldopam (CHEBI:5002) has role dopamine agonist (CHEBI:51065)
fenoldopam (CHEBI:5002) has role dopaminergic antagonist (CHEBI:48561)
fenoldopam (CHEBI:5002) has role renoprotective agent (CHEBI:231911)
fenoldopam (CHEBI:5002) has role vasodilator agent (CHEBI:35620)
fenoldopam (CHEBI:5002) has role α-adrenergic agonist (CHEBI:35569)
fenoldopam (CHEBI:5002) is a benzazepine (CHEBI:35676)
IUPAC Name 
6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
INNs  Source
fenoldopamChemIDplus
fénoldopamChEBI
fenoldopamumChemIDplus
Synonyms  Source
CarlacorChEMBL
SK-82526ChEMBL
SK&F-82526ChEMBL
Manual XrefsDatabases
1153DrugCentral
C07693KEGG COMPOUND
D07946KEGG DRUG
DB00800DrugBank
DE2751258Patent
FenoldopamWikipedia
LSM-1609LINCS
US4197297Patent
Registry NumbersSources
CAS:67227-56-9ChemIDplus
Citations