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CHEBI:49681 - 4,5,6,7-tetrabromobenzimidazole

ChEBI IDCHEBI:49681
ChEBI Name4,5,6,7-tetrabromobenzimidazole
Stars
DefinitionA member of the class of benzimidazoles that is 1H-benzimidazole substituted by bromo groups at positions 4, 5, 6, and 7. It is an ATP competitive casein kinase 2 inhibitor.
Last Modified15 January 2025
DownloadsMolfile
FormulaC7H2Br4N2
Net Charge0
Average Mass433.723
Monoisotopic Mass429.69515
SMILESBrc1c(Br)c(Br)c2ncnc2c1Br
InChIInChI=1S/C7H2Br4N2/c8-2-3(9)5(11)7-6(4(2)10)12-1-13-7/h1H,(H,12,13)
InChIKeyLOEIRDBRYBHAJB-UHFFFAOYSA-N
Roles Classification
Biological Roles:
apoptosis inducer  Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor  An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine.
ChEBI Ontology
Outgoing Relation(s)
4,5,6,7-tetrabromobenzimidazole (CHEBI:49681) has role apoptosis inducer (CHEBI:68495)
4,5,6,7-tetrabromobenzimidazole (CHEBI:49681) has role EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor (CHEBI:50925)
4,5,6,7-tetrabromobenzimidazole (CHEBI:49681) is a benzimidazoles (CHEBI:22715)
4,5,6,7-tetrabromobenzimidazole (CHEBI:49681) is a organobromine compound (CHEBI:37141)
IUPAC Name 
4,5,6,7-tetrabromo-1H-benzimidazole
Synonyms  Source
4,5,6,7-tetrabromo-benzimidazolePDBeChem
TBBzChEBI
casein kinase II inhibitor XIIChEBI
4,5,6,7-1H-tetrabromobenzimidazoleChEBI
4,5,6,7-tetrabromo-1H-1,3-benzodiazoleChEBI
Manual XrefsDatabases
K17PDBeChem
Registry NumbersSources
CAS:577779-57-8ChEBI
Citations