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CHEBI:48558 - roxindole

ChEBI IDCHEBI:48558
ChEBI Nameroxindole
Stars
Last Modified6 July 2016
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC23H26N2O
Net Charge0
Average Mass346.474
Monoisotopic Mass346.20451
SMILESOc1ccc2ncc(CCCCN3CC=C(c4ccccc4)CC3)c2c1
InChIInChI=1S/C23H26N2O/c26-21-9-10-23-22(16-21)20(17-24-23)8-4-5-13-25-14-11-19(12-15-25)18-6-2-1-3-7-18/h1-3,6-7,9-11,16-17,24,26H,4-5,8,12-15H2
InChIKeyHGEYJZMMUGWEOT-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
alpha-adrenergic antagonist  An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Applications:
alpha-adrenergic antagonist  An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
ChEBI Ontology
Outgoing Relation(s)
roxindole (CHEBI:48558) has role serotonergic drug (CHEBI:48278)
roxindole (CHEBI:48558) has role α-adrenergic antagonist (CHEBI:37890)
roxindole (CHEBI:48558) is a indoles (CHEBI:24828)
IUPAC Name 
3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol
INNs  Source
roxindoleWHO MedNet
roxindolWHO MedNet
roxindoleWHO MedNet
roxindolumWHO MedNet
Synonyms  Source
3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-olChemIDplus
3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-olIUPHAR
Manual XrefsDatabases
RoxindoleWikipedia
Registry NumbersSources
Beilstein:5855538Beilstein
CAS:112192-04-8ChemIDplus