CHEBI:48538 - apomorphine

ChEBI IDCHEBI:48538
ChEBI Nameapomorphine
Stars
Secondary ChEBI IDCHEBI:94845
Last Modified23 April 2020
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC17H17NO2
Net Charge0
Average Mass267.328
Monoisotopic Mass267.12593
SMILES[H][C@@]12Cc3ccc(O)c(O)c3-c3cccc(c31)CCN2C
InChIInChI=1S/C17H17NO2/c1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12/h2-6,13,19-20H,7-9H2,1H3/t13-/m1/s1
InChIKeyVMWNQDUVQKEIOC-CYBMUJFWSA-N
Wikipedia
Roles Classification
Biological Roles:
dopamine agonist  A drug that binds to and activates dopamine receptors.
alpha-adrenergic drug  Any drug that acts on an α-adrenergic receptor.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Applications:
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
emetic  Any agent that induces nausea and vomiting.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
dopamine agonist  A drug that binds to and activates dopamine receptors.
alpha-adrenergic drug  Any drug that acts on an α-adrenergic receptor.
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
antidyskinesia agent  Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
apomorphine (CHEBI:48538) has parent hydride aporphine (CHEBI:35643)
apomorphine (CHEBI:48538) has role antidyskinesia agent (CHEBI:66956)
apomorphine (CHEBI:48538) has role antiparkinson drug (CHEBI:48407)
apomorphine (CHEBI:48538) has role antipsychotic agent (CHEBI:35476)
apomorphine (CHEBI:48538) has role dopamine agonist (CHEBI:51065)
apomorphine (CHEBI:48538) has role emetic (CHEBI:149552)
apomorphine (CHEBI:48538) has role neuroprotective agent (CHEBI:63726)
apomorphine (CHEBI:48538) has role serotonergic drug (CHEBI:48278)
apomorphine (CHEBI:48538) has role vasodilator agent (CHEBI:35620)
apomorphine (CHEBI:48538) has role α-adrenergic drug (CHEBI:48539)
apomorphine (CHEBI:48538) is a aporphine alkaloid (CHEBI:134209)
Incoming Relation(s)
apomorphine hydrochloride (CHEBI:31228) has part apomorphine (CHEBI:48538)
IUPAC Name 
6aβ-aporphine-10,11-diol
Synonyms  Source
(−)-10,11-dihydroxyaporphineChemIDplus
6a.beta.-aporphine-10,11-diolChEMBL
(6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diolIUPAC
APL-130277ChEMBL
ApomorphinChEBI
apomorphineIUPHAR
Manual XrefsDatabases
228DrugCentral
2964VSDB
ApomorphineWikipedia
DB00714DrugBank
LSM-25611LINCS
Registry NumbersSources
Beilstein:29319Beilstein
Beilstein:3653944Beilstein
CAS:58-00-4NIST Chemistry WebBook
CAS:58-00-4ChemIDplus
Citations