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CHEBI:48416 - olmesartan

ChEBI IDCHEBI:48416
ChEBI Nameolmesartan
Stars
Last Modified25 February 2016
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC24H26N6O3
Net Charge0
Average Mass446.511
Monoisotopic Mass446.20664
SMILESCCCc1nc(C(C)(C)O)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2)cc1
InChIInChI=1S/C24H26N6O3/c1-4-7-19-25-21(24(2,3)33)20(23(31)32)30(19)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)22-26-28-29-27-22/h5-6,8-13,33H,4,7,14H2,1-3H3,(H,31,32)(H,26,27,28,29)
InChIKeyVTRAEEWXHOVJFV-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
Applications:
angiotensin receptor antagonist  A hormone antagonist that blocks angiotensin receptors.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
ChEBI Ontology
Outgoing Relation(s)
olmesartan (CHEBI:48416) has role angiotensin receptor antagonist (CHEBI:61016)
olmesartan (CHEBI:48416) has role antihypertensive agent (CHEBI:35674)
olmesartan (CHEBI:48416) is a biphenylyltetrazole (CHEBI:48420)
IUPAC Name 
4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid
Synonyms  Source
4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acidIUPAC
4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acidIUPHAR
olmesartanIUPHAR
Manual XrefsDatabases
DB00275DrugBank
LSM-5893LINCS
OlmesartanWikipedia
Registry NumbersSources
Beilstein:7502669Beilstein
CAS:144689-24-7ChemIDplus