EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:46557 - zoledronic acid

ChEBI IDCHEBI:46557
ChEBI Namezoledronic acid
Stars
DefinitionAn imidazole compound having a 2,2-bis(phosphono)-2-hydroxyethane-1-yl substituent at the 1-position.
Last Modified8 October 2021
DownloadsMolfile
FormulaC5H10N2O7P2
Net Charge0
Average Mass272.090
Monoisotopic Mass271.99632
SMILESO=P(O)(O)C(O)(Cn1ccnc1)P(=O)(O)O
InChIInChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)
InChIKeyXRASPMIURGNCCH-UHFFFAOYSA-N
Wikipedia
Roles Classification
Application:
bone density conservation agent  An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
ChEBI Ontology
Outgoing Relation(s)
zoledronic acid (CHEBI:46557) has role bone density conservation agent (CHEBI:50646)
zoledronic acid (CHEBI:46557) is a 1,1-bis(phosphonic acid) (CHEBI:77383)
zoledronic acid (CHEBI:46557) is a imidazoles (CHEBI:24780)
IUPAC Name 
[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)
INN  Source
zoledronic acidChemIDplus
Synonyms  Source
ZOLEDRONIC ACIDPDBeChem
(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acidChemIDplus
(1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acidChemIDplus
ZOLDrugBank
Brand Name  Source
ReclastDrugBank
Manual XrefsDatabases
ZOLPDBeChem
US4939130Patent
DB00399DrugBank
D08689KEGG DRUG
Zoledronic_acidWikipedia
2868DrugCentral
61986ChemSpider
Registry NumbersSources
Beilstein:9205049Beilstein
Gmelin:2609374Gmelin
CAS:118072-93-8ChemIDplus
CAS:118072-93-8KEGG DRUG
CAS:118072-93-8DrugBank
Citations