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CHEBI:4653 - dipyridamole

ChEBI IDCHEBI:4653
ChEBI Namedipyridamole
Stars
DefinitionA pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Last Modified22 February 2017
DownloadsMolfile
FormulaC24H40N8O4
Net Charge0
Average Mass504.636
Monoisotopic Mass504.31725
SMILESOCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCO)nc(N3CCCCC3)c2n1
InChIInChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
InChIKeyIZEKFCXSFNUWAM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
EC 3.5.4.4 (adenosine deaminase) inhibitor  An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of adenosine deaminase (EC 3.5.4.4).
Applications:
platelet aggregation inhibitor  A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
vasodilator agent  A drug used to cause dilation of the blood vessels.
ChEBI Ontology
Outgoing Relation(s)
dipyridamole (CHEBI:4653) has role adenosine phosphodiesterase inhibitor (CHEBI:50444)
dipyridamole (CHEBI:4653) has role EC 3.5.4.4 (adenosine deaminase) inhibitor (CHEBI:50445)
dipyridamole (CHEBI:4653) has role platelet aggregation inhibitor (CHEBI:50427)
dipyridamole (CHEBI:4653) has role vasodilator agent (CHEBI:35620)
dipyridamole (CHEBI:4653) is a piperidines (CHEBI:26151)
dipyridamole (CHEBI:4653) is a pyrimidopyrimidine (CHEBI:48514)
dipyridamole (CHEBI:4653) is a tertiary amino compound (CHEBI:50996)
dipyridamole (CHEBI:4653) is a tetrol (CHEBI:33573)
IUPAC Name 
2,2',2'',2'''-[(4,8-dipiperidin-1-ylpyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetraethanol
INNs  Source
dipyridamoleChemIDplus
dipyridamolumChemIDplus
Synonyms  Source
DipyridamineDrugBank
DipyudamineDrugBank
DypyridamolDrugBank
Brand Names  Source
CardoxinChEBI
Cleridium 150DrugBank
CurantylDrugBank
dipiridamolChemIDplus
PersantinDrugBank
Manual XrefsDatabases
924DrugCentral
D00302KEGG DRUG
DB00975DrugBank
DipyridamoleWikipedia
GB807826Patent
LSM-3927LINCS
US3031450Patent
Registry NumbersSources
Beilstein:0068373Beilstein
Reaxys:68373Reaxys
CAS:58-32-2ChemIDplus
Citations