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CHEBI:4601 - diloxanide furoate

Default Structure
ChEBI IDCHEBI:4601
ChEBI Namediloxanide furoate
Stars
DefinitionA carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis.
Last Modified28 April 2021
DownloadsMolfile
FormulaC14H11Cl2NO4
Net Charge0
Average Mass328.151
Monoisotopic Mass327.00651
SMILESCN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1
InChIInChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
InChIKeyBDYYDXJSHYEDGB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antiamoebic agent  An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
ChEBI Ontology
Outgoing Relation(s)
diloxanide furoate (CHEBI:4601) has role antiamoebic agent (CHEBI:171664)
diloxanide furoate (CHEBI:4601) has role prodrug (CHEBI:50266)
diloxanide furoate (CHEBI:4601) is a carboxylic ester (CHEBI:33308)
diloxanide furoate (CHEBI:4601) is a furans (CHEBI:24129)
diloxanide furoate (CHEBI:4601) is a organochlorine compound (CHEBI:36683)
diloxanide furoate (CHEBI:4601) is a tertiary carboxamide (CHEBI:140326)
IUPAC Name 
4-[(dichloroacetyl)(methyl)amino]phenyl furan-2-carboxylate
Synonyms  Source
8073 CBChemIDplus
CB 8073ChemIDplus
diloxanide furoateKEGG COMPOUND
diloxanid furoateDrugCentral
entamide furoateDrugCentral
Brand Names  Source
AmebiazolChemIDplus
DichlofurazolDrugCentral
DiclofurazolChemIDplus
FuramideChemIDplus
FurentominChemIDplus
HistomibalChemIDplus
Manual XrefsDatabases
18400ChemSpider
896DrugCentral
C07637KEGG COMPOUND
D02480KEGG DRUG
DB14638DrugBank
DiloxanideWikipedia
HMDB0015684HMDB
LSM-2223LINCS
Registry NumbersSources
CAS:3736-81-0ChemIDplus
Citations