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CHEBI:4601 - diloxanide furoate

ChEBI IDCHEBI:4601
ChEBI Namediloxanide furoate
Stars
DefinitionA carboxylic ester resulting from the formal condensation of the carboxy group of furan-2-carboxylic acid with the hydroxy group of 2,2-dichloro-N-(4-hydroxyphenyl)-N-methylacetamide. It is a drug used for the treatment of asymptomatic amebiasis.
Last Modified28 April 2021
DownloadsMolfile
FormulaC14H11Cl2NO4
Net Charge0
Average Mass328.151
Monoisotopic Mass327.00651
SMILESCN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1
InChIInChI=1S/C14H11Cl2NO4/c1-17(13(18)12(15)16)9-4-6-10(7-5-9)21-14(19)11-3-2-8-20-11/h2-8,12H,1H3
InChIKeyBDYYDXJSHYEDGB-UHFFFAOYSA-N
Wikipedia
Roles Classification
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
antiamoebic agent  An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae.
ChEBI Ontology
Outgoing Relation(s)
diloxanide furoate (CHEBI:4601) has role antiamoebic agent (CHEBI:171664)
diloxanide furoate (CHEBI:4601) has role prodrug (CHEBI:50266)
diloxanide furoate (CHEBI:4601) is a carboxylic ester (CHEBI:33308)
diloxanide furoate (CHEBI:4601) is a furans (CHEBI:24129)
diloxanide furoate (CHEBI:4601) is a organochlorine compound (CHEBI:36683)
diloxanide furoate (CHEBI:4601) is a tertiary carboxamide (CHEBI:140326)
IUPAC Name 
4-[(dichloroacetyl)(methyl)amino]phenyl furan-2-carboxylate
Synonyms  Source
diloxanide furoateKEGG COMPOUND
entamide furoateDrugCentral
diloxanid furoateDrugCentral
8073 CBChemIDplus
CB 8073ChemIDplus
Brand Names  Source
DiclofurazolChemIDplus
DichlofurazolDrugCentral
FuramideChemIDplus
FurentominChemIDplus
AmebiazolChemIDplus
MiforonChemIDplus
Manual XrefsDatabases
C07637KEGG COMPOUND
D02480KEGG DRUG
LSM-2223LINCS
896DrugCentral
HMDB0015684HMDB
DB14638DrugBank
DiloxanideWikipedia
18400ChemSpider
Registry NumbersSources
CAS:3736-81-0ChemIDplus
Citations