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CHEBI:45367 - rifabutin
| Formula | C46H62N4O11 |
| Net Charge | 0 |
| Average Mass | 847.019 |
| Monoisotopic Mass | 846.44151 |
| SMILES | CO[C@H]1/C=C/O[C@@]2(C)Oc3c(C)c(O)c4c(c3C2=O)C2=NC3(CCN(CC(C)C)CC3)NC2=C(NC(=O)/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C4=O |
| InChI | InChI=1S/C46H62N4O11/c1-22(2)21-50-18-16-46(17-19-50)48-34-31-32-39(54)28(8)42-33(31)43(56)45(10,61-42)59-20-15-30(58-11)25(5)41(60-29(9)51)27(7)38(53)26(6)37(52)23(3)13-12-14-24(4)44(57)47-36(40(32)55)35(34)49-46/h12-15,20,22-23,25-27,30,37-38,41,49,52-54H,16-19,21H2,1-11H3,(H,47,57)/b13-12+,20-15+,24-14-/t23-,25+,26+,27+,30-,37-,38+,41+,45-/m0/s1 |
| InChIKey | ATEBXHFBFRCZMA-VXTBVIBXSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. |
| Applications: | antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| rifabutin (CHEBI:45367) has role anti-HIV agent (CHEBI:64946) |
| rifabutin (CHEBI:45367) has role antibacterial agent (CHEBI:33282) |
| rifabutin (CHEBI:45367) has role antifungal agent (CHEBI:35718) |
| rifabutin (CHEBI:45367) has role antiinfective agent (CHEBI:35441) |
| rifabutin (CHEBI:45367) has role antitubercular agent (CHEBI:33231) |
| rifabutin (CHEBI:45367) is a rifamycins (CHEBI:26580) |
| INN | Source |
|---|---|
| rifabutina | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1,4-Dihydro-1-deoxy-1',4-didehydro-5'-(2-methylpropyl)-1-oxorifamycin XIV | ChemIDplus |
| 4-Deoxo-3,4-(2-spiro(N-isobutyl-4-piperidyl)-2,5-dihydro-1H-imidazo)-rifamycin S | ChemIDplus |
| 4-N-isobutylspiropiperidylrifamycin S | ChemIDplus |
| LM 427 | ChEMBL |
| LM-427 | ChEMBL |
| Mycobutin (TN) | KEGG DRUG |
| Brand Name | Source |
|---|---|
| Rifabutin component of talicia | ChEMBL |
| Citations |
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