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CHEBI:4495 - diazoxide
| Formula | C8H7ClN2O2S |
| Net Charge | 0 |
| Average Mass | 230.676 |
| Monoisotopic Mass | 229.99168 |
| SMILES | CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |
| InChI | InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) |
| InChIKey | GDLBFKVLRPITMI-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. sodium channel blocker An agent that inhibits sodium influx through cell membranes. K-ATP channel agonist A compound which acts as an agonist at the ATP-sensitive K+ channel. anti-obesity agent Any substance which is used to reduce or control weight. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. |
| Applications: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. cardiotonic drug A drug that has a strengthening effect on the heart or that can increase cardiac output. diuretic An agent that promotes the excretion of urine through its effects on kidney function. hyperglycemic agent A drug which increases the blood glucose level. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. vasodilator agent A drug used to cause dilation of the blood vessels. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. hypoglycemic agent A drug which lowers the blood glucose level. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| diazoxide (CHEBI:4495) has role anti-obesity agent (CHEBI:74518) |
| diazoxide (CHEBI:4495) has role antidepressant (CHEBI:35469) |
| diazoxide (CHEBI:4495) has role antihypertensive agent (CHEBI:35674) |
| diazoxide (CHEBI:4495) has role bronchodilator agent (CHEBI:35523) |
| diazoxide (CHEBI:4495) has role cardiotonic drug (CHEBI:38147) |
| diazoxide (CHEBI:4495) has role diuretic (CHEBI:35498) |
| diazoxide (CHEBI:4495) has role hyperglycemic agent (CHEBI:76916) |
| diazoxide (CHEBI:4495) has role hypoglycemic agent (CHEBI:35526) |
| diazoxide (CHEBI:4495) has role K-ATP channel agonist (CHEBI:64338) |
| diazoxide (CHEBI:4495) has role sodium channel blocker (CHEBI:38633) |
| diazoxide (CHEBI:4495) has role sympathomimetic agent (CHEBI:35524) |
| diazoxide (CHEBI:4495) has role vasodilator agent (CHEBI:35620) |
| diazoxide (CHEBI:4495) has role β-adrenergic agonist (CHEBI:35522) |
| diazoxide (CHEBI:4495) is a benzothiadiazine (CHEBI:50265) |
| diazoxide (CHEBI:4495) is a organic molecular entity (CHEBI:50860) |
| diazoxide (CHEBI:4495) is a organochlorine compound (CHEBI:36683) |
| diazoxide (CHEBI:4495) is a sulfone (CHEBI:35850) |
| IUPAC Name |
|---|
| 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide |
| INNs | Source |
|---|---|
| diazoxide | ChemIDplus |
| diazoxido | ChemIDplus |
| diazoxidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| Diazossido | ChemIDplus |
| Diazoxide | KEGG COMPOUND |
| Eudemine injection | ChEMBL |
| NSC-64198 | ChEMBL |
| NSC-76130 | ChEMBL |
| SCH 6783 | ChEMBL |
| Brand Names | Source |
|---|---|
| Eudemine | DrugBank |
| Eudimine | ChEMBL |
| Mutabase | ChEMBL |
| Proglycem | ChEMBL |
| Citations |
|---|