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CHEBI:4495 - diazoxide
| Formula | C8H7ClN2O2S |
| Net Charge | 0 |
| Average Mass | 230.676 |
| Monoisotopic Mass | 229.99168 |
| SMILES | CC1=Nc2ccc(Cl)cc2S(=O)(=O)N1 |
| InChI | InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) |
| InChIKey | GDLBFKVLRPITMI-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. anti-obesity agent Any substance which is used to reduce or control weight. K-ATP channel agonist A compound which acts as an agonist at the ATP-sensitive K+ channel. sodium channel blocker An agent that inhibits sodium influx through cell membranes. |
| Applications: | beta-adrenergic agonist An agent that selectively binds to and activates β-adrenergic receptors. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. hypoglycemic agent A drug which lowers the blood glucose level. sympathomimetic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. cardiotonic drug A drug that has a strengthening effect on the heart or that can increase cardiac output. bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. hyperglycemic agent A drug which increases the blood glucose level. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. vasodilator agent A drug used to cause dilation of the blood vessels. diuretic An agent that promotes the excretion of urine through its effects on kidney function. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| diazoxide (CHEBI:4495) has role anti-obesity agent (CHEBI:74518) |
| diazoxide (CHEBI:4495) has role antidepressant (CHEBI:35469) |
| diazoxide (CHEBI:4495) has role antihypertensive agent (CHEBI:35674) |
| diazoxide (CHEBI:4495) has role bronchodilator agent (CHEBI:35523) |
| diazoxide (CHEBI:4495) has role cardiotonic drug (CHEBI:38147) |
| diazoxide (CHEBI:4495) has role diuretic (CHEBI:35498) |
| diazoxide (CHEBI:4495) has role hyperglycemic agent (CHEBI:76916) |
| diazoxide (CHEBI:4495) has role hypoglycemic agent (CHEBI:35526) |
| diazoxide (CHEBI:4495) has role K-ATP channel agonist (CHEBI:64338) |
| diazoxide (CHEBI:4495) has role sodium channel blocker (CHEBI:38633) |
| diazoxide (CHEBI:4495) has role sympathomimetic agent (CHEBI:35524) |
| diazoxide (CHEBI:4495) has role vasodilator agent (CHEBI:35620) |
| diazoxide (CHEBI:4495) has role β-adrenergic agonist (CHEBI:35522) |
| diazoxide (CHEBI:4495) is a benzothiadiazine (CHEBI:50265) |
| diazoxide (CHEBI:4495) is a organochlorine compound (CHEBI:36683) |
| diazoxide (CHEBI:4495) is a sulfone (CHEBI:35850) |
| IUPAC Name |
|---|
| 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide |
| INNs | Source |
|---|---|
| diazoxide | ChemIDplus |
| diazoxido | ChemIDplus |
| diazoxidum | ChemIDplus |
| Synonyms | Source |
|---|---|
| Diazossido | ChemIDplus |
| Diazoxide | KEGG COMPOUND |
| Eudemine injection | ChEMBL |
| NSC-64198 | ChEMBL |
| NSC-76130 | ChEMBL |
| SCH 6783 | ChEMBL |
| Brand Names | Source |
|---|---|
| Eudemine | DrugBank |
| Eudimine | ChEMBL |
| Mutabase | ChEMBL |
| Proglycem | ChEMBL |
| Citations |
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