EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:4462 - dexamethasone sodium phosphate
| Formula | C22H28FO8P.2Na |
| Net Charge | 0 |
| Average Mass | 516.410 |
| Monoisotopic Mass | 516.13012 |
| SMILES | [H][C@@]12C[C@@H](C)[C@](O)(C(=O)COP(=O)([O-])[O-])[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@@]21C.[Na+].[Na+] |
| InChI | InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1 |
| InChIKey | PLCQGRYPOISRTQ-FCJDYXGNSA-L |
| Roles Classification |
|---|
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. antiviral agent A substance that destroys or inhibits replication of viruses. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. glucocorticoid receptor agonist An agonist that selectively binds to and activates a glucocorticoid receptor. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-asthmatic agent Any compound that has anti-asthmatic effects. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. anti-inflammatory agent Any compound that has anti-inflammatory effects. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. antipsoriatic A drug used to treat psoriasis. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| dexamethasone sodium phosphate (CHEBI:4462) has part dexamethasone phosphate(2−) (CHEBI:68638) |
| dexamethasone sodium phosphate (CHEBI:4462) has role anti-anaemic agent (CHEBI:75835) |
| dexamethasone sodium phosphate (CHEBI:4462) has role anti-asthmatic agent (CHEBI:65023) |
| dexamethasone sodium phosphate (CHEBI:4462) has role anti-inflammatory agent (CHEBI:67079) |
| dexamethasone sodium phosphate (CHEBI:4462) has role anti-ulcer drug (CHEBI:49201) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antimicrobial agent (CHEBI:33281) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antineoplastic agent (CHEBI:35610) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antipsoriatic (CHEBI:50748) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antirheumatic drug (CHEBI:35842) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antitubercular agent (CHEBI:33231) |
| dexamethasone sodium phosphate (CHEBI:4462) has role antiviral agent (CHEBI:22587) |
| dexamethasone sodium phosphate (CHEBI:4462) has role dermatologic drug (CHEBI:50177) |
| dexamethasone sodium phosphate (CHEBI:4462) has role glucocorticoid receptor agonist (CHEBI:63562) |
| dexamethasone sodium phosphate (CHEBI:4462) has role immunosuppressive agent (CHEBI:35705) |
| dexamethasone sodium phosphate (CHEBI:4462) has role ophthalmology drug (CHEBI:66981) |
| dexamethasone sodium phosphate (CHEBI:4462) is a organic sodium salt (CHEBI:38700) |
| IUPAC Name |
|---|
| disodium 9-fluoro-11β,17-dihydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-yl phosphate |
| Synonyms | Source |
|---|---|
| Dalalone | KEGG DRUG |
| Dexamethasone 21-(disodium phosphate) | ChemIDplus |
| Dexamethasone 21-phosphate disodium salt | ChEMBL |
| Dexamethasone sodium phosphate | KEGG DRUG |
| NSC-756722 | ChEMBL |
| Sodium dexamethasone phosphate | ChemIDplus |
| Brand Names | Source |
|---|---|
| Ak-dex | ChEMBL |
| Decadron phosphate | ChEMBL |
| Dexabene | ChEMBL |
| Dexacen-4 | ChEMBL |
| Dexacort | ChEMBL |
| Dexair | ChEMBL |
| Citations |
|---|