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CHEBI:44485 - N-ethylmaleimide

ChEBI IDCHEBI:44485
ChEBI NameN-ethylmaleimide
Stars
ASCII NameN-ethylmaleimide
DefinitionA member of the class of maleimides that is the N-ethyl derivative of maleimide.
Secondary ChEBI IDsCHEBI:7269, CHEBI:44483
Last Modified23 April 2020
DownloadsMolfile
FormulaC6H7NO2
Net Charge0
Average Mass125.127
Monoisotopic Mass125.04768
SMILESCCN1C(=O)C=CC1=O
InChIInChI=1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3
InChIKeyHDFGOPSGAURCEO-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor  An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP+), EC 1.3.1.8.
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor  An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122).
EC 2.7.1.1 (hexokinase) inhibitor  An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate.
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
ChEBI Ontology
Outgoing Relation(s)
N-ethylmaleimide (CHEBI:44485) has functional parent maleimide (CHEBI:16072)
N-ethylmaleimide (CHEBI:44485) has role anticoronaviral agent (CHEBI:149553)
N-ethylmaleimide (CHEBI:44485) has role EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP+)] inhibitor (CHEBI:78377)
N-ethylmaleimide (CHEBI:44485) has role EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor (CHEBI:77115)
N-ethylmaleimide (CHEBI:44485) has role EC 2.7.1.1 (hexokinase) inhibitor (CHEBI:78366)
N-ethylmaleimide (CHEBI:44485) is a maleimides (CHEBI:55417)
IUPAC Name 
1-ethyl-1H-pyrrole-2,5-dione
Synonyms  Source
N-EthylmaleimideKEGG COMPOUND
EthylmaleimideChemIDplus
NEMNIST Chemistry WebBook
N-ETHYLMALEIMIDEPDBeChem
UniProt Name  Source
N-ethylmaleimideUniProt
Manual XrefsDatabases
C02441KEGG COMPOUND
NEQPDBeChem
DB02967DrugBank
N-ETHYLMALEIMIDEMetaCyc
N-EthylmaleimideWikipedia
LSM-4219LINCS
Registry NumbersSources
Beilstein:112448Beilstein
Gmelin:405614Gmelin
Reaxys:112448Reaxys
CAS:128-53-0KEGG COMPOUND
CAS:128-53-0ChemIDplus
CAS:128-53-0NIST Chemistry WebBook
Citations