EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:41948 - eflornithine
| Formula | C6H12F2N2O2 |
| Net Charge | 0 |
| Average Mass | 182.170 |
| Monoisotopic Mass | 182.08668 |
| SMILES | NCCCC(N)(C(=O)O)C(F)F |
| InChI | InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12) |
| InChIKey | VLCYCQAOQCDTCN-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. |
| Applications: | trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. hypoglycemic agent A drug which lowers the blood glucose level. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| eflornithine (CHEBI:41948) has functional parent ornithine (CHEBI:18257) |
| eflornithine (CHEBI:41948) has role antileishmanial agent (CHEBI:70868) |
| eflornithine (CHEBI:41948) has role antineoplastic agent (CHEBI:35610) |
| eflornithine (CHEBI:41948) has role hypoglycemic agent (CHEBI:35526) |
| eflornithine (CHEBI:41948) has role trypanocidal drug (CHEBI:36335) |
| eflornithine (CHEBI:41948) is a fluoroamino acid (CHEBI:24068) |
| eflornithine (CHEBI:41948) is a α-amino acid (CHEBI:33704) |
| Incoming Relation(s) |
| eflornithine hydrochloride monohydrate (CHEBI:4762) has part eflornithine (CHEBI:41948) |
| IUPAC Names |
|---|
| 2,5-diamino-2-(difluoromethyl)pentanoic acid |
| 2-(difluoromethyl)ornithine |
| INN | Source |
|---|---|
| eflornitina | WHO MedNet |
| Synonyms | Source |
|---|---|
| alpha-(Difluoromethyl)-DL-ornithine | DrugCentral |
| ALPHA-DIFLUOROMETHYLORNITHINE | PDBeChem |
| DFMO | ChemIDplus |
| DL-Ornithine, 2-(difluoromethyl)- | KEGG COMPOUND |
| Eflornithine | KEGG COMPOUND |
| α-difluoromethylornithine | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| Reaxys:2250529 | Reaxys |
| Beilstein:2250529 | Beilstein |
| CAS:67037-37-0 | KEGG COMPOUND |
| CAS:67037-37-0 | ChemIDplus |
| CAS:70052-12-9 | ChemIDplus |
| Citations |
|---|