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CHEBI:40823 - (aminooxy)acetic acid

ChEBI IDCHEBI:40823
ChEBI Name(aminooxy)acetic acid
Stars
DefinitionA member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of γ-aminobutyric acid in tissues.
Last Modified15 October 2020
DownloadsMolfile
FormulaC2H5NO3
Net Charge0
Average Mass91.066
Monoisotopic Mass91.02694
SMILESNOCC(=O)O
InChIInChI=1S/C2H5NO3/c3-6-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyNQRKYASMKDDGHT-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor  An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19).
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor  An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine β-synthase (EC 4.2.1.22).
Applications:
nootropic agent  Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
(aminooxy)acetic acid (CHEBI:40823) has role anticonvulsant (CHEBI:35623)
(aminooxy)acetic acid (CHEBI:40823) has role EC 2.6.1.19 (4-aminobutyrate—2-oxoglutarate transaminase) inhibitor (CHEBI:63674)
(aminooxy)acetic acid (CHEBI:40823) has role EC 4.2.1.22 (cystathionine β-synthase) inhibitor (CHEBI:63157)
(aminooxy)acetic acid (CHEBI:40823) has role nootropic agent (CHEBI:66980)
(aminooxy)acetic acid (CHEBI:40823) is a amino acid (CHEBI:33709)
(aminooxy)acetic acid (CHEBI:40823) is a hydroxylamines (CHEBI:24709)
(aminooxy)acetic acid (CHEBI:40823) is a monocarboxylic acid (CHEBI:25384)
(aminooxy)acetic acid (CHEBI:40823) is conjugate acid of (aminooxy)acetate (CHEBI:157642)
Incoming Relation(s)
(aminooxy)acetate (CHEBI:157642) is conjugate base of (aminooxy)acetic acid (CHEBI:40823)
IUPAC Name 
(aminooxy)acetic acid
Synonyms  Source
2-(aminooxy)acetic acidIUPAC
aminooxyacetic acidChemIDplus
AOAAChemIDplus
2-aminooxyethanoic acidPDBeChem
(carboxymethoxy)amineChemIDplus
carboxymethoxyamineDrugBank
Manual XrefsDatabases
AOAPDBeChem
280ChemSpider
DB02079DrugBank
CARBOXYMETHOXYLAMINEMetaCyc
Aminooxyacetic_acidWikipedia
Registry NumbersSources
Reaxys:878238Reaxys
CAS:645-88-5ChemIDplus
Citations