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CHEBI:40823 - (aminooxy)acetic acid

Default Structure
ChEBI IDCHEBI:40823
ChEBI Name(aminooxy)acetic acid
Stars
DefinitionA member of the class of hydroxylamines that is acetic acid substituted at postion 2 by an aminooxy group. It is a compound which inhibits aminobutyrate aminotransferase activity in vivo, resulting in increased levels of γ-aminobutyric acid in tissues.
Last Modified15 October 2020
DownloadsMolfile
FormulaC2H5NO3
Net Charge0
Average Mass91.066
Monoisotopic Mass91.02694
SMILESNOCC(=O)O
InChIInChI=1S/C2H5NO3/c3-6-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyNQRKYASMKDDGHT-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor  An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine β-synthase (EC 4.2.1.22).
EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor  An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate—2-oxoglutarate transaminase (EC 2.6.1.19).
Applications:
anticonvulsant  A drug used to prevent seizures or reduce their severity.
nootropic agent  Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
ChEBI Ontology
Outgoing Relation(s)
(aminooxy)acetic acid (CHEBI:40823) has role anticonvulsant (CHEBI:35623)
(aminooxy)acetic acid (CHEBI:40823) has role EC 2.6.1.19 (4-aminobutyrate—2-oxoglutarate transaminase) inhibitor (CHEBI:63674)
(aminooxy)acetic acid (CHEBI:40823) has role EC 4.2.1.22 (cystathionine β-synthase) inhibitor (CHEBI:63157)
(aminooxy)acetic acid (CHEBI:40823) has role nootropic agent (CHEBI:66980)
(aminooxy)acetic acid (CHEBI:40823) is a amino acid (CHEBI:33709)
(aminooxy)acetic acid (CHEBI:40823) is a hydroxylamines (CHEBI:24709)
(aminooxy)acetic acid (CHEBI:40823) is a monocarboxylic acid (CHEBI:25384)
(aminooxy)acetic acid (CHEBI:40823) is conjugate acid of (aminooxy)acetate (CHEBI:157642)
Incoming Relation(s)
(aminooxy)acetate (CHEBI:157642) is conjugate base of (aminooxy)acetic acid (CHEBI:40823)
IUPAC Name 
(aminooxy)acetic acid
Synonyms  Source
2-(aminooxy)acetic acidIUPAC
2-aminooxyethanoic acidPDBeChem
aminooxyacetic acidChemIDplus
AOAChEBI
AOAAChemIDplus
(carboxymethoxy)amineChemIDplus
Manual XrefsDatabases
280ChemSpider
Aminooxyacetic_acidWikipedia
AOAPDBeChem
CARBOXYMETHOXYLAMINEMetaCyc
DB02079DrugBank
Registry NumbersSources
Reaxys:878238Reaxys
CAS:645-88-5ChemIDplus
Citations