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CHEBI:40279 - allopurinol
| Formula | C5H4N4O |
| Net Charge | 0 |
| Average Mass | 136.114 |
| Monoisotopic Mass | 136.03851 |
| SMILES | Oc1ncnc2nncc12 |
| InChI | InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10) |
| InChIKey | OFCNXPDARWKPPY-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. |
| Biological Roles: | anti-obesity agent Any substance which is used to reduce or control weight. antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. EC 1.17.3.2 (xanthine oxidase) inhibitor An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). |
| Applications: | hepatoprotective agent Any compound that is able to prevent damage to the liver. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. vulnerary A drug used in treating and healing of wounds. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. antileishmanial agent An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. anti-inflammatory agent Any compound that has anti-inflammatory effects. hypoglycemic agent A drug which lowers the blood glucose level. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| allopurinol (CHEBI:40279) has parent hydride 1H-pyrazolo[4,3-d]pyrimidine (CHEBI:50092) |
| allopurinol (CHEBI:40279) has role anti-inflammatory agent (CHEBI:67079) |
| allopurinol (CHEBI:40279) has role anti-obesity agent (CHEBI:74518) |
| allopurinol (CHEBI:40279) has role antihypertensive agent (CHEBI:35674) |
| allopurinol (CHEBI:40279) has role antileishmanial agent (CHEBI:70868) |
| allopurinol (CHEBI:40279) has role antimetabolite (CHEBI:35221) |
| allopurinol (CHEBI:40279) has role antineoplastic agent (CHEBI:35610) |
| allopurinol (CHEBI:40279) has role antipsychotic agent (CHEBI:35476) |
| allopurinol (CHEBI:40279) has role antitubercular agent (CHEBI:33231) |
| allopurinol (CHEBI:40279) has role cardiovascular drug (CHEBI:35554) |
| allopurinol (CHEBI:40279) has role EC 1.17.3.2 (xanthine oxidase) inhibitor (CHEBI:35634) |
| allopurinol (CHEBI:40279) has role gout suppressant (CHEBI:35845) |
| allopurinol (CHEBI:40279) has role hepatoprotective agent (CHEBI:62868) |
| allopurinol (CHEBI:40279) has role hypoglycemic agent (CHEBI:35526) |
| allopurinol (CHEBI:40279) has role radical scavenger (CHEBI:48578) |
| allopurinol (CHEBI:40279) has role vulnerary (CHEBI:73336) |
| allopurinol (CHEBI:40279) is a nucleobase analogue (CHEBI:67142) |
| allopurinol (CHEBI:40279) is a organic heterobicyclic compound (CHEBI:27171) |
| Incoming Relation(s) |
| allopurinol riboside (CHEBI:74074) has functional parent allopurinol (CHEBI:40279) |
| IUPAC Name |
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| 1H-pyrazolo[3,4-d]pyrimidin-4-ol |
| Synonyms | Source |
|---|---|
| 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one | ChemIDplus |
| 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one | ChemIDplus |
| 1H-Pyrazolo(3,4-d)pyrimidin-4-ol | ChemIDplus |
| 4-HPP | NIST Chemistry WebBook |
| 4H-Pyrazolo(3,4-d)pyrimidin-4-one | ChemIDplus |
| 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine | ChemIDplus |
| Brand Names | Source |
|---|---|
| Allopurinol component of duzallo | ChEMBL |
| Aloral | ChEMBL |
| Aluline 100 | ChEMBL |
| Aluline 300 | ChEMBL |
| Caplenal | ChEMBL |
| Cosuric | ChEMBL |
| Citations |
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