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CHEBI:40154 - 5-fluorouridine

Default Structure
ChEBI IDCHEBI:40154
ChEBI Name5-fluorouridine
Stars
DefinitionAn organofluorine compound that is uridine bearing a fluoro substituent at position 5 on the uracil ring.
Secondary ChEBI IDsCHEBI:46390, CHEBI:73164
Last Modified3 April 2020
SubmitterJohnny Lloyd
DownloadsMolfile
FormulaC9H11FN2O6
Net Charge0
Average Mass262.193
Monoisotopic Mass262.06011
SMILESO=c1nc(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1F
InChIInChI=1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChIKeyFHIDNBAQOFJWCA-UAKXSSHOSA-N
Roles Classification
Biological Role:
mutagen  An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
5-fluorouridine (CHEBI:40154) has role antineoplastic agent (CHEBI:35610)
5-fluorouridine (CHEBI:40154) has role mutagen (CHEBI:25435)
5-fluorouridine (CHEBI:40154) is a organofluorine compound (CHEBI:37143)
5-fluorouridine (CHEBI:40154) is a uridines (CHEBI:27242)
Incoming Relation(s)
2'-O-methyl-5-fluorouridine (CHEBI:760577) has functional parent 5-fluorouridine (CHEBI:40154)
Synonyms  Source
5-Fluorouracil 1beta-D-ribofuranosideDrugBank
5-Fluoro-uridineDrugBank
5-FLUOROURIDINEPDBeChem
NSC-146604ChEMBL
UniProt Name  Source
5-fluorouridineUniProt
Manual XrefsDatabases
5UDPDBeChem
C16633KEGG COMPOUND
CPD0-2367MetaCyc
DB01629DrugBank
EP1600153Patent
EP927045Patent
US2005208122Patent
US5734042Patent
US6372725Patent
Registry NumbersSources
Reaxys:33662Reaxys
Beilstein:33662Beilstein
Gmelin:466575Gmelin
CAS:316-46-1ChemIDplus
CAS:316-46-1KEGG COMPOUND
CAS:316-46-1KEGG DRUG
Citations