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CHEBI:38431 - 1,4-benzodiazepine

ChEBI IDCHEBI:38431
ChEBI Name1,4-benzodiazepine
Stars
Last Modified14 July 2008
DownloadsMolfile
FormulaC9H8N2
Net Charge0
Average Mass144.177
Monoisotopic Mass144.06875
SMILESC1=CNc2ccccc2C=N1
InChIInChI=1S/C9H8N2/c1-2-4-9-8(3-1)7-10-5-6-11-9/h1-7,11H
InChIKeyGUJAGMICFDYKNR-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
1,4-benzodiazepine (CHEBI:38431) is a benzodiazepine (CHEBI:22720)
1,4-benzodiazepine (CHEBI:38431) is a mancude organic heterobicyclic parent (CHEBI:35570)
Incoming Relation(s)
4'-chlorodiazepam (CHEBI:232375) is a 1,4-benzodiazepine (CHEBI:38431)
IUPAC Name 
1H-1,4-benzodiazepine
Registry NumbersSources
CAS:264-64-2ChemIDplus