CHEBI:38010 - apazone

ChEBI IDCHEBI:38010
ChEBI Nameapazone
Stars
DefinitionA member of the class of benzotriazines that is 1,2-dihydro-1,2,4-benzotriazine bearing a dimethylamino substitutent at position 3 and a methyl substituent at position 7 and in which the nitrogens at positions 1 and 2 are both acylated by a carboxy group of propylmalonic acid.
Last Modified22 February 2017
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC16H20N4O2
Net Charge0
Average Mass300.362
Monoisotopic Mass300.15863
SMILESCCCC1C(=O)N2C(N(C)C)=Nc3ccc(C)cc3N2C1=O
InChIInChI=1S/C16H20N4O2/c1-5-6-11-14(21)19-13-9-10(2)7-8-12(13)17-16(18(3)4)20(19)15(11)22/h7-9,11H,5-6H2,1-4H3
InChIKeyMPHPHYZQRGLTBO-UHFFFAOYSA-N
Roles Classification
Applications:
uricosuric drug  A gout suppressant that acts directly on the renal tubule to increase the excretion of uric acid, thus reducing its concentrations in plasma.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
apazone (CHEBI:38010) has parent hydride 1,2,4-benzotriazine (CHEBI:38011)
apazone (CHEBI:38010) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
apazone (CHEBI:38010) has role uricosuric drug (CHEBI:35841)
apazone (CHEBI:38010) is a benzotriazines (CHEBI:51361)
IUPAC Name 
5-(dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione
INNs  Source
azapropazonaChemIDplus
azapropazonumChemIDplus
Synonyms  Source
1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazineChemIDplus
3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazineChemIDplus
5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dioneChemIDplus
AzapropazoneChemIDplus
AzapropazonChemIDplus
Manual XrefsDatabases
D02966KEGG DRUG
FR1440629Patent
US3349088Patent
US348024Patent
DB07402DrugBank
LSM-5132LINCS
266DrugCentral
Registry NumbersSources
Reaxys:623763Reaxys
CAS:13539-59-8ChemIDplus
CAS:13539-59-8KEGG DRUG