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CHEBI:3755 - clomipramine hydrochloride

ChEBI IDCHEBI:3755
ChEBI Nameclomipramine hydrochloride
Stars
DefinitionA hydrochloride resulting from the reaction of equimolar amounts of clomipramine and hydrogen chloride. One of the more sedating tricyclic antidepressants, it is used for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Last Modified23 April 2020
DownloadsMolfile
FormulaC19H23ClN2.HCl
Net Charge0
Average Mass351.321
Monoisotopic Mass350.13165
SMILESCN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc21.Cl
InChIInChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChIKeyWIMWMKZEIBHDTH-UHFFFAOYSA-N
Roles Classification
Biological Roles:
anticoronaviral agent  Any antiviral agent which inhibits the activity of coronaviruses.
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
Applications:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
ChEBI Ontology
Outgoing Relation(s)
clomipramine hydrochloride (CHEBI:3755) has part clomipramine(1+) (CHEBI:64209)
clomipramine hydrochloride (CHEBI:3755) has role anticoronaviral agent (CHEBI:149553)
clomipramine hydrochloride (CHEBI:3755) has role antidepressant (CHEBI:35469)
clomipramine hydrochloride (CHEBI:3755) has role serotonergic antagonist (CHEBI:48279)
clomipramine hydrochloride (CHEBI:3755) has role serotonergic drug (CHEBI:48278)
clomipramine hydrochloride (CHEBI:3755) is a hydrochloride (CHEBI:36807)
IUPAC Name 
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
Synonyms  Source
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-aminium chlorideIUPAC
chloroimipramine monohydrochlorideChemIDplus
clomipramine HClChemIDplus
3-chloroimipramine hydrochlorideChemIDplus
clomipramine monohydrochlorideChEBI
Brand Name  Source
AnafranilKEGG DRUG
Manual XrefsDatabases
D00811KEGG DRUG
DB01242DrugBank
1812VSDB
Registry NumbersSources
Reaxys:4168494Reaxys
CAS:17321-77-6KEGG DRUG
CAS:17321-77-6ChemIDplus