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CHEBI:3732 - clarithromycin

Default Structure
ChEBI IDCHEBI:3732
ChEBI Nameclarithromycin
Stars
DefinitionThe 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis.
Secondary ChEBI IDsCHEBI:41676, CHEBI:442148, CHEBI:670147
Last Modified22 February 2017
DownloadsMolfile
FormulaC38H69NO13
Net Charge0
Average Mass747.964
Monoisotopic Mass747.47689
SMILES[H][C@]1(O[C@H]2[C@H](C)[C@@H](O[C@]3([H])O[C@H](C)C[C@H](N(C)C)[C@H]3O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]2C)C[C@@](C)(OC)[C@@H](O)[C@H](C)O1
InChIInChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChIKeyAGOYDEPGAOXOCK-KCBOHYOISA-N
Roles Classification
Chemical Role:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Biological Roles:
protein synthesis inhibitor  A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
antibacterial drug  A drug used to treat or prevent bacterial infections.
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
Application:
antibacterial drug  A drug used to treat or prevent bacterial infections.
ChEBI Ontology
Outgoing Relation(s)
clarithromycin (CHEBI:3732) has role antibacterial drug (CHEBI:36047)
clarithromycin (CHEBI:3732) has role environmental contaminant (CHEBI:78298)
clarithromycin (CHEBI:3732) has role protein synthesis inhibitor (CHEBI:48001)
clarithromycin (CHEBI:3732) has role xenobiotic (CHEBI:35703)
clarithromycin (CHEBI:3732) is a macrolide antibiotic (CHEBI:25105)
IUPAC Name 
O6-methylerythromycin
INNs  Source
clarithromycinChemIDplus
clarithromycinaChemIDplus
clarithromycineChemIDplus
clarithromycinumChemIDplus
Synonyms  Source
6-O-methylerythromycinChemIDplus
6-O-methylerythromycin AChemIDplus
CLADrugBank
ClarithromycinKEGG COMPOUND
CLARITHROMYCINPDBeChem
Manual XrefsDatabases
668DrugCentral
C06912KEGG COMPOUND
CTYPDBeChem
D00276KEGG DRUG
DB01211DrugBank
EP41355Patent
LMPK04000014LIPID MAPS
LSM-5606LINCS
US4331803Patent
Registry NumbersSources
Reaxys:3581974Reaxys
CAS:81103-11-9ChemIDplus
CAS:81103-11-9KEGG COMPOUND
Citations