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CHEBI:3724 - citalopram hydrobromide
| ChEBI ID | CHEBI:3724 |
| ChEBI Name | citalopram hydrobromide |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)-citalopram hydrobromide and escitalopram hydrobromide. It is used for the treatment of depression. Only the (S)-enantiomer, (escitalopram hydrobromide) is active. |
| Last Modified | 21 February 2014 |
| Roles Classification |
|---|
| Biological Role: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| Applications: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| citalopram hydrobromide (CHEBI:3724) has part (R)-citalopram hydrobromide (CHEBI:77422) |
| citalopram hydrobromide (CHEBI:3724) has part escitalopram hydrobromide (CHEBI:77423) |
| citalopram hydrobromide (CHEBI:3724) has role antidepressant (CHEBI:35469) |
| citalopram hydrobromide (CHEBI:3724) has role serotonin uptake inhibitor (CHEBI:50949) |
| citalopram hydrobromide (CHEBI:3724) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| 3-[5-cyano-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-1-yl]-N,N-dimethylpropan-1-aminium bromide |
| Synonyms | Source |
|---|---|
| 1-(3-(dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile monohydrobromide | ChemIDplus |
| 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile monohydrobromide | ChemIDplus |
| 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile monohydrobromide | ChemIDplus |
| 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile hydrobromide | IUPAC |
| Brand Name | Source |
|---|---|
| Celexa | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D00822 | KEGG DRUG |
| Registry Numbers | Sources |
|---|---|
| Beilstein:5368282 | Beilstein |
| CAS:59729-32-7 | ChemIDplus |
| Citations |
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