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CHEBI:3650 - chlorpropamide

Default Structure
ChEBI IDCHEBI:3650
ChEBI Namechlorpropamide
Stars
DefinitionAn N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
Secondary ChEBI IDCHEBI:108516
Last Modified22 February 2017
DownloadsMolfile
FormulaC10H13ClN2O3S
Net Charge0
Average Mass276.745
Monoisotopic Mass276.03354
SMILESCCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
InChIInChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
InChIKeyRKWGIWYCVPQPMF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
insulin secretagogue  A secretagogue that causes the secretion of insulin.
Application:
hypoglycemic agent  A drug which lowers the blood glucose level.
ChEBI Ontology
Outgoing Relation(s)
chlorpropamide (CHEBI:3650) has role hypoglycemic agent (CHEBI:35526)
chlorpropamide (CHEBI:3650) has role insulin secretagogue (CHEBI:90415)
chlorpropamide (CHEBI:3650) is a N-sulfonylurea (CHEBI:76983)
chlorpropamide (CHEBI:3650) is a monochlorobenzenes (CHEBI:83403)
INNs  Source
chlorpropamideChemIDplus
chlorpropamideWHO MedNet
chlorpropamidumChemIDplus
clorpropamidaChemIDplus
Synonyms  Source
1-(p-chlorobenzenesulfonyl)-3-propylureaNIST Chemistry WebBook
1-(p-chlorophenylsulfonyl)-3-propylureaNIST Chemistry WebBook
1-propyl-3-(p-chlorobenzenesulfonyl)ureaNIST Chemistry WebBook
4-chloro-N-((propylamino)carbonyl)benzenesulfonamideChEMBL
4-chloro-N-[(propylamino)carbonyl]benzenesulfonamideChEMBL
CHLORPROPAMIDEChEMBL
Manual XrefsDatabases
622DrugCentral
ChlorpropamideWikipedia
D00271KEGG DRUG
DB00672DrugBank
GB853555Patent
HMDB0014810HMDB
LSM-6695LINCS
US3349124Patent
Registry NumbersSources
Reaxys:2218363Reaxys
CAS:94-20-2NIST Chemistry WebBook
CAS:94-20-2ChemIDplus
CAS:94-20-2KEGG DRUG
Citations