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CHEBI:35847 - tenidap

ChEBI IDCHEBI:35847
ChEBI Nametenidap
Stars
Last Modified22 February 2017
SubmitterMarcus Ennis
DownloadsMolfile
FormulaC14H9ClN2O3S
Net Charge0
Average Mass320.757
Monoisotopic Mass320.00224
SMILESNC(=O)N1C(=O)/C(=C(\O)c2cccs2)c2cc(Cl)ccc21
InChIInChI=1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,18H,(H2,16,20)/b12-11-
InChIKeyLXIKEPCNDFVJKC-QXMHVHEDSA-N
Roles Classification
Biological Role:
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor  A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
Application:
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
tenidap (CHEBI:35847) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544)
tenidap (CHEBI:35847) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
tenidap (CHEBI:35847) is a indoles (CHEBI:24828)
tenidap (CHEBI:35847) is a organochlorine compound (CHEBI:36683)
tenidap (CHEBI:35847) is a thiophenes (CHEBI:26961)
tenidap (CHEBI:35847) is a ureas (CHEBI:47857)
IUPAC Name 
(3Z)-5-chloro-3-[hydroxy(2-thienyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-1-carboxamide
Synonyms  Source
TenidapChemIDplus
(Z)-5-Chloro-3-(alpha-hydroxy-2-thenylidene)-2-oxo-1-indolinecarboxamideChemIDplus
Manual XrefsDatabases
4728DrugCentral
Registry NumbersSources
CAS:120210-48-2ChemIDplus