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CHEBI:34992 - Talampanel
| Formula | C19H19N3O3 |
| Net Charge | 0 |
| Average Mass | 337.379 |
| Monoisotopic Mass | 337.14264 |
| SMILES | CC(=O)N1N=C(c2ccc(N)cc2)c2cc3c(cc2C[C@H]1C)OCO3 |
| InChI | InChI=1S/C19H19N3O3/c1-11-7-14-8-17-18(25-10-24-17)9-16(14)19(21-22(11)12(2)23)13-3-5-15(20)6-4-13/h3-6,8-9,11H,7,10,20H2,1-2H3/t11-/m1/s1 |
| InChIKey | JACAAXNEHGBPOQ-LLVKDONJSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. anticonvulsant A drug used to prevent seizures or reduce their severity. antiparkinson drug A drug used in the treatment of Parkinson's disease. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| Talampanel (CHEBI:34992) has role anticonvulsant (CHEBI:35623) |
| Talampanel (CHEBI:34992) has role antineoplastic agent (CHEBI:35610) |
| Talampanel (CHEBI:34992) has role antiparkinson drug (CHEBI:48407) |
| Talampanel (CHEBI:34992) is a benzodiazepine (CHEBI:22720) |
| Talampanel (CHEBI:34992) is a benzodioxoles (CHEBI:38298) |
| Talampanel (CHEBI:34992) is a organic molecular entity (CHEBI:50860) |
| Synonyms | Source |
|---|---|
| GYKI-53773 | ChEMBL |
| Ly300164 | ChEMBL |
| LY-300164 | ChEMBL |
| (-)-talampanel | ChEMBL |
| Talampanel | KEGG COMPOUND |
| Citations |
|---|