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CHEBI:34942 - R-L3

ChEBI IDCHEBI:34942
ChEBI NameR-L3
Stars
Last Modified28 July 2014
DownloadsMolfile
FormulaC25H20FN3O
Net Charge0
Average Mass397.453
Monoisotopic Mass397.15904
SMILESCN1C(=O)[C@@H](Cc2cnc3ccccc23)N=C(c2ccccc2F)c2ccccc21
InChIInChI=1S/C25H20FN3O/c1-29-23-13-7-4-10-19(23)24(18-9-2-5-11-20(18)26)28-22(25(29)30)14-16-15-27-21-12-6-3-8-17(16)21/h2-13,15,22,27H,14H2,1H3/t22-/m1/s1
InChIKeyCGBANSGENFERAT-JOCHJYFZSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
R-L3 (CHEBI:34942) is a benzodiazepine (CHEBI:22720)
Synonym  Source
R-L3KEGG COMPOUND
Manual XrefsDatabases
C13824KEGG COMPOUND