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CHEBI:3441 - carvedilol
| Formula | C24H26N2O4 |
| Net Charge | 0 |
| Average Mass | 406.482 |
| Monoisotopic Mass | 406.18926 |
| SMILES | COc1ccccc1OCCNCC(O)COc1cccc2nc3ccccc3c12 |
| InChI | InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3 |
| InChIKey | OGHNVEJMJSYVRP-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. |
| Applications: | alpha-adrenergic antagonist An agent that binds to but does not activate α-adrenergic receptors thereby blocking the actions of endogenous or exogenous α-adrenergic agonists. α-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. vasodilator agent A drug used to cause dilation of the blood vessels. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| carvedilol (CHEBI:3441) has role antihypertensive agent (CHEBI:35674) |
| carvedilol (CHEBI:3441) has role cardiovascular drug (CHEBI:35554) |
| carvedilol (CHEBI:3441) has role vasodilator agent (CHEBI:35620) |
| carvedilol (CHEBI:3441) has role α-adrenergic antagonist (CHEBI:37890) |
| carvedilol (CHEBI:3441) has role β-adrenergic antagonist (CHEBI:35530) |
| carvedilol (CHEBI:3441) is a carbazoles (CHEBI:48513) |
| carvedilol (CHEBI:3441) is a secondary alcohol (CHEBI:35681) |
| carvedilol (CHEBI:3441) is a secondary amino compound (CHEBI:50995) |
| IUPAC Name |
|---|
| 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol |
| INNs | Source |
|---|---|
| carvedilol | WHO MedNet |
| carvedilol | ChemIDplus |
| carvédilol | WHO MedNet |
| carvedilolum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol | ChemIDplus |
| Carvedilol | KEGG COMPOUND |
| SKF 105517 | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| 522 | DrugCentral |
| C06875 | KEGG COMPOUND |
| Carvedilol | Wikipedia |
| D00255 | KEGG DRUG |
| DB01136 | DrugBank |
| DE2815926 | Patent |
| HMDB0015267 | HMDB |
| LSM-1310 | LINCS |
| US4503067 | Patent |
| Registry Numbers | Sources |
|---|---|
| Reaxys:1514452 | Reaxys |
| CAS:72956-09-3 | ChemIDplus |
| CAS:72956-09-3 | KEGG COMPOUND |
| Citations |
|---|